16-Hydroxypregnenolone

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 16-Hydroxypregnenolone
• 英文别名: 1-(3,16-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
• 化学式: C₂₁H₃₂O₃
• 分子量: 332.5
• InChiKey: ZAKJZPQDUPCXSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

ADMET

代谢

1-(3,16-二羟基-10,13-二甲基-2,3,4,7,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯[a]菲-17-基)乙酮是孕烯醇酮的人类已知代谢物。

1-(3,16-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone is a known human metabolite of pregnenolone.

来源:NORMAN Suspect List Exchange

文献信息

• Cross-Reactive Sensor Arrays And Methods of Use
  申请人：The Trustees Of Columbia University In The City Of New York

  公开号：US20140187437A1

  公开（公告）日：2014-07-03

  Disclosed herein are methods and compositions directed to the construction of aptamer-based receptors and cross-reactive sensor arrays of such receptors and the use of the same in disease detection and management.
• [EN] CROSS-REACTIVE SENSOR ARRAYS AND METHODS OF USES<br/>[FR] GROUPEMENTS DE CAPTEURS À RÉACTION CROISÉE ET PROCÉDÉS D'UTILISATION
  申请人：UNIV COLUMBIA

  公开号：WO2013119260A1

  公开（公告）日：2013-08-15

  Disclosed herein are methods and compositions directed to the construction of aptamer-based receptors and cross-reactive sensor arrays of such receptors and the use of the same in disease detection and management.