4-(4-Methyl-cyclohex-1-enyl)-phenol | 32960-73-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(4-Methyl-cyclohex-1-enyl)-phenol
• 英文别名: (+/-)-4-hydroxy-1-(4-methyl-cyclohexen-(1)-yl)-benzene；(+/-)-4-Hydroxy-1-(4-methyl-cyclohexen-(1)-yl)-benzol；4-(4-methylcyclohexen-1-yl)-phenol；4-(4-Methylcyclohexen-1-yl)phenol
• CAS: 32960-73-9
• 化学式: C₁₃H₁₆O
• 分子量: 188.269
• InChiKey: BFRSIGOLHWSGOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-(4-Methyl-cyclohex-1-enyl)-phenol 、 alkaline earth salt of/the/ methylsulfuric acid 生成 4-(4-甲基环己基)苯酚
  参考文献：
  名称：

  Abdurassulewa; Achmedow, Zhurnal Obshchei Khimii, 1963, vol. 33, p. 3733

  摘要：

  DOI：
• 作为产物：
  描述：

  4-methyl-1,1-bis(4'-hydroxyphenyl)cyclohexane 生成 4-(4-Methyl-cyclohex-1-enyl)-phenol
  参考文献：
  名称：

  Condensations of Ketones with Phenols

  摘要：

  DOI：

  10.1021/ja01871a032

文献信息

• Condensations of Ketones with Phenols
  作者：Martin E. McGreal、Victor. Niederl、Joseph B. Niederl

  DOI：10.1021/ja01871a032

  日期：1939.2
• Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation
  申请人：Marquette University

  公开号：US20210340155A1

  公开（公告）日：2021-11-04

  Disclosed are substituted (4′-hydroxylphenyl)cycloalkane compounds and substituted (4′-hydroxylphenyl)cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered for treating diseases associated with ER activity, such as neurological, psychiatric, and/or cell proliferative diseases and disorders as well as for enhancing memory consolidation in subjects in need thereof.
• US4505837A
  申请人：——

  公开号：US4505837A

  公开（公告）日：1985-03-19
• Abdurassulewa; Achmedow, Zhurnal Obshchei Khimii, 1963, vol. 33, p. 3733
  作者：Abdurassulewa、Achmedow

  DOI：——

  日期：——