4,5,5-Triphenyl-pent-4-en-2-on | 7593-09-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4,5,5-Triphenyl-pent-4-en-2-on
• 英文别名: 4,5,5-Triphenylpent-4-en-2-one
• CAS: 7593-09-1
• 化学式: C₂₃H₂₀O
• 分子量: 312.411
• InChiKey: CGKRKWSPCUFVSZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4,5,5-Triphenyl-pent-4-en-2-on 、 3-(2-噻吩基)苯甲醛 、 二异丙醇胺 在 盐酸 作用下， 以 乙腈 、 水 为溶剂， 反应 11.5h， 生成 1-[Bis(2-hydroxypropyl)amino]-5,6,6-triphenyl-1-(3-thiophen-2-ylphenyl)hex-5-en-3-one
  参考文献：
  名称：

  一种曼尼希碱季铵盐耐高温酸化缓蚀剂的制 备方法及应用

  摘要：

  本发明公开了一种曼尼希碱季铵盐耐高温酸化缓蚀剂的制备方法及应用，制备如下：(1)将胺类物质吲哚、二苯甲基哌啶、二苯基乙胺、二苄胺或者二异丙醇胺溶于有机溶剂中，缓慢加入醛类物质3‑(2‑噻吩基)苯甲醛或肉桂醛，放入恒温水浴锅中，60‑80℃下搅拌反应1‑3h，然后将酮类物质苄叉丙酮、二苯乙烯丙酮或1,1‑二苯基丙酮加入其中，调节PH值至3—4，反应7‑10h，冷却至室温，减压蒸馏除去溶剂，得到曼尼希碱；(2)将曼尼希碱溶于有机溶剂中，加入季铵化试剂氯甲基萘、氯化苄或者三苯氯甲烷，在70‑90℃反应14‑16h，冷却至室温，减压蒸馏。本发明简单可行，原料无毒，安全环保，制备的酸化缓蚀剂对油气井碳钢的酸腐蚀有明显的抑制作用。

  公开号：

  CN109810040B

文献信息

• Process for preparing Mannich base quaternary ammonium salt high-temperature resistant corrosion inhibitor and applications thereof
  申请人：SOUTHWEST PETROLEUM UNIVERSITY

  公开号：US11161811B2

  公开（公告）日：2021-11-02

  The present invention discloses a process for preparing a Mannich base quaternary ammonium salt high-temperature resistant corrosion inhibitor and applications thereof. The preparation process comprises the following steps: (1) dissolve an amine substance indole, benzhydrylpiperidine, diphenylethylamine, dibenzylamine or diisopropanolamine into an organic solvent, slowly add an aldehyde substance 3-(2-thienyl)benzaldehyde or cinnamaldehyde, then place in a constant-temperature water bath, stir to react at 60-80° C. for 1 to 3 hours, then add a ketone substance benzalacetone, diphenylstyryl acetone or 1,1-diphenylacetone, adjust the reaction system pH to 3 to 4 using a hydrochloric acid solution, and then react for 7 to 10 hours; after cooled to room temperature, perform distillation under a reduced pressure to remove the solvent, to obtain a Mannich base; (2) dissolve the Mannich base in an organic solvent, add quaternizing reagent chloromethylnaphthalene, benzyl chloride or triphenylchloromethane, then react at 70-90° C. for 14-16 h, after cooled to room temperature, perform distillation under a reduced pressure. The process is simple and feasible, and its raw material is non-toxic, safe and environmental-friendly, and the prepared corrosion inhibitor has obvious resistance to the acid corrosion of carbon steels in oil-gas wells.

  本发明公开了一种曼尼希基季铵盐耐高温缓蚀剂的制备工艺及其应用。该制备工艺包括以下步骤：(1) 将胺类物质吲哚、苯氢哌啶、二苯乙胺、二苄胺或二异丙醇胺溶于有机溶剂中，缓慢加入醛类物质 3-(2-噻吩基)苯甲醛或肉桂醛，然后置于恒温水浴中，在 60-80° C 下搅拌反应1 至 3 小时，然后加入酮类物质苯并丙酮、二苯乙烯基丙酮或 1,1-二苯基丙酮，用盐酸溶液将反应体系的 pH 值调至 3 至 4，再反应 7 至 10 小时；冷却至室温后，减压蒸馏除去溶剂，得到曼尼希碱；(2) 将曼尼希碱溶解于有机溶剂中，加入季铵化试剂氯甲基萘、氯化苄或三苯基氯甲烷，在 70-90°C 下反应 14-16 小时，冷却至室温后，减压蒸馏除去溶剂，得到曼尼希碱。14-16 小时，冷却至室温后，减压蒸馏。该工艺简单可行，原料无毒、安全、环保，制备的缓蚀剂对油气井碳钢的酸腐蚀具有明显的抗性。
• PROCESS FOR PREPARING MANNICH BASE QUATERNARY AMMONIUM SALT HIGH-TEMPERATURE RESISTANT CORROSION INHIBITOR AND APPLICATIONS THEREOF
  申请人：SOUTHWEST PETROLEUM UNIVERSITY

  公开号：US20200331856A1

  公开（公告）日：2020-10-22

  The present invention discloses a process for preparing a Mannich base quaternary ammonium salt high-temperature resistant corrosion inhibitor and applications thereof. The preparation process comprises the following steps: (1) dissolve an amine substance indole, benzhydrylpiperidine, diphenylethylamine, dibenzylamine or diisopropanolamine into an organic solvent, slowly add an aldehyde substance 3-(2-thienyl)benzaldehyde or cinnamaldehyde, then place in a constant-temperature water bath, stir to react at 60-80° C. for 1 to 3 hours, then add a ketone substance benzalacetone, diphenylstyryl acetone or 1,1-diphenylacetone, adjust the reaction system pH to 3 to 4 using a hydrochloric acid solution, and then react for 7 to 10 hours; after cooled to room temperature, perform distillation under a reduced pressure to remove the solvent, to obtain a Mannich base; (2) dissolve the Mannich base in an organic solvent, add quaternizing reagent chloromethylnaphthalene, benzyl chloride or triphenylchloromethane, then react at 70-90° C. for 14-16 h, after cooled to room temperature, perform distillation under a reduced pressure. The process is simple and feasible, and its raw material is non-toxic, safe and environmental-friendly, and the prepared corrosion inhibitor has obvious resistance to the acid corrosion of carbon steels in oil-gas wells.
• 一种曼尼希碱季铵盐耐高温酸化缓蚀剂的制 备方法及应用
  申请人：西南石油大学

  公开号：CN109810040B

  公开（公告）日：2020-02-18

  本发明公开了一种曼尼希碱季铵盐耐高温酸化缓蚀剂的制备方法及应用，制备如下：(1)将胺类物质吲哚、二苯甲基哌啶、二苯基乙胺、二苄胺或者二异丙醇胺溶于有机溶剂中，缓慢加入醛类物质3‑(2‑噻吩基)苯甲醛或肉桂醛，放入恒温水浴锅中，60‑80℃下搅拌反应1‑3h，然后将酮类物质苄叉丙酮、二苯乙烯丙酮或1,1‑二苯基丙酮加入其中，调节PH值至3—4，反应7‑10h，冷却至室温，减压蒸馏除去溶剂，得到曼尼希碱；(2)将曼尼希碱溶于有机溶剂中，加入季铵化试剂氯甲基萘、氯化苄或者三苯氯甲烷，在70‑90℃反应14‑16h，冷却至室温，减压蒸馏。本发明简单可行，原料无毒，安全环保，制备的酸化缓蚀剂对油气井碳钢的酸腐蚀有明显的抑制作用。