acetyltriisopropylsilane | 121675-51-2

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: acetyltriisopropylsilane
• 英文别名: Silane, acetyltris(1-methylethyl)-；1-tri(propan-2-yl)silylethanone
• CAS: 121675-51-2
• 化学式: C₁₁H₂₄OSi
• 分子量: 200.396
• InChiKey: HYJSILVJOHEFLY-UHFFFAOYSA-N

物化性质

• 沸点：
  59 °C(Press: 0.2 Torr)
• 密度：
  0.820±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.79
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  acetyltriisopropylsilane 在 dimethyl sulfide borane 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以82%的产率得到1-(triisopropylsilyl)ethanol
  参考文献：
  名称：

  1- and 2-(trialkylsilyl)ethanols: new silyl reagents from tin, lithium, and boron chemistry

  摘要：

  DOI：

  10.1021/jo00278a014
• 作为产物：
  描述：

  三异丙基氯硅烷 在 盐酸 作用下， 以 丙酮 为溶剂， 反应 14.5h， 生成 acetyltriisopropylsilane
  参考文献：
  名称：

  1- and 2-(trialkylsilyl)ethanols: new silyl reagents from tin, lithium, and boron chemistry

  摘要：

  DOI：

  10.1021/jo00278a014

文献信息

• Novel Silicon-Based Patchouli Odorants of the Trialkyl(1-hydroxy-1-methylethyl)silane Type: Design, Synthesis, and Olfactory Properties
  作者：Astrid Sunderkötter、Sabine Lorenzen、Reinhold Tacke、Philip Kraft

  DOI：10.1002/chem.201000549

  日期：2010.7.5

  synthesized and studied for their olfactory properties. All of the silanes studied exhibit at least one of the main patchouli odor descriptors ‘woody,’ ‘earthy,’ and ‘camphoraceous,’ and some even exhibit all of them. The silanes MeR2SiC(OH)Me2 (12) and R3SiC(OH)Me2 (14) (R=cyclopropyl) were found to resemble natural patchouli oil most closely, with an even lower odor threshold than the natural lead

  叔丁基（1-羟基-1-甲基乙基）二甲基硅烷（5），一硅杂取代的开环衍生物的最近报道广藿香引线结构（4A - [R *，8α - [R *） - 1,1,8a-trimethyldecahydronaphthalene甲基-4a-醇（4），和一些相关的三烷基（1-羟基-1-甲基乙基）硅烷和进一步的衍生物，化合物8 - 24，用不同的硅结合的取代基（ME等，我PR，ç PR，吨卜，i Bu，c Pent，乙烯基，SiMe 3）合成并研究其嗅觉特性。所研究的所有硅烷均表现出至少一种主要的广香气味描述符“木质”，“土”和“樟脑”，甚至有些甚至全部表现出来。发现硅烷MeR 2 SiC（OH）Me 2（12）和R 3 SiC（OH）Me 2（14）（R =环丙基）最接近天然广patch香油，气味阈值比天然铅更低结构（-）-广atch香酚（1）。为了完成该结构与气味的关系研究，需要使用12和14的碳类似物（Si
• Simchen, Gerhard; Jonas, Simon, Journal fur Praktische Chemie - Chemiker-Zeitung, 1998, vol. 340, # 6, p. 506 - 512
  作者：Simchen, Gerhard、Jonas, Simon

  DOI：——

  日期：——
• Essentially homochiral 1-silyl alcohols from the reduction of aliphatic acylsilanes with chlorodiisopinocampheylborane
  作者：John A Soderquist、Charles L Anderson、Edgar I Miranda、Isaac Rivera、George W Kabalka

  DOI：10.1016/s0040-4039(00)97704-9

  日期：1990.1
• Facile synthesis of a novel class of organometalloid-containing ligands, the sila-β-diketones: preparation and physical and structural characterization of the copper(II) complexes, Cu[R′C(O)CHC(O)SiR3]2
  作者：Kulbinder K Banger、Silvana C Ngo、Seiichiro Higashiya、Rolf U Claessen、Kenneth S Bousman、Poay N Lim、Paul J Toscano、John T Welch

  DOI：10.1016/s0022-328x(03)00393-0

  日期：2003.7

  The substitution of a carbon atom by silicon provides an attractive, novel approach to modification of the thermal stability and volatility of metal-organic chemical vapor deposition precursors supported by beta-diketonate ancillary ligands. The low temperature reaction of the lithium enolates of acetyltrialkylsilanes with acyl chlorides affords the sila-beta-diketones, R'C(O)CH2C(O)SiR3 (R' = Me, Et, n-Pr, i-Pr, n-Bu, i-Bu, s-Bu, t-Bu; SiR3 = SiMe3, SiEt3, SiMe2(t-Bu), SiMe2(t-hexyl), Si(i-Pr)A in good yields. Multinuclear NMR studies suggest that the sila-beta-diketones exist as the enolic tautomer with a vinylsilane isomeric structure. Homoleptic Cu(II) sila-beta-diketonate complexes were prepared in a first pass study to evaluate how precursor performance is affected by modulation of the peripheral substituents in the ligands. Thermal analyses, (TGA, DSC) show that the silylated Cu(II) precursors (SiR3 = SiMe3; R' = t-Bu or i-Bu) have greater volatility than the corresponding carbon analogues. Some of the new Cu(11) complexes exist as liquids or low melting solids, which are preferred states for industrial deposition processes. X-ray diffraction studies of selected copper complexes showed them to have typical, square planar geometry; calculations of molecular volumes suggest that packing in the solid-state is less efficient for the silicon-containing complexes than for the non-silylated analogues. (C) 2003 Elsevier Science B.V. All rights reserved.
• Acetylsilane O-silylcyanohydrins as precursors to .alpha.-silyl ketones and .beta.-siloxy-N,N-bissilylenamines
  作者：Robert F. Cunico、Chia P. Kuan

  DOI：10.1021/jo00302a029

  日期：1990.7