peroxo nitrate radical | 126588-37-2

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 非金属氧阴离子化合物
• 英文名称: peroxo nitrate radical
• 英文别名: trans-peroxynitrate；cis-peroxynitrate；OO.NO cis；Oxidoperoxidonitrogen(.)
• CAS: 126588-37-2
• 化学式: NO₃
• 分子量: 62.0049
• InChiKey: XPGFERQQLIGTRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  亚硝酸氧盐 在 sodium chloride 作用下， 以 aq. phosphate buffer 为溶剂， 生成 peroxo nitrate radical
  参考文献：
  名称：

  Electrochemical Detection of Nitric Oxide and Peroxynitrite Anion in Microchannels at Highly Sensitive Platinum-Black Coated Electrodes. Application to ROS and RNS Mixtures prior to Biological Investigations

  摘要：

  The electrochemical detection of nitric oxide (NO center dot) and peroxynitrite anion (ONOO-) was investigated at Pt-black electrodes in microchannels. Owing to the high reactivity of these species under conditions close to physiological media, kinetic parameters were determined before evaluating the detection performances from synthetic solutions. Highly sensitive and stable Pt-black electrodes allowed detection limits down to 30 nM (NO center dot) and 40 nM (ONOO-) to be reached with very high sensitivities. As NO center dot and ONOO- are two relevant biological molecules involved in oxidative stress their simultaneous detections with other major molecules like hydrogen peroxide and nitrite were also performed and validated experimentally at pH 8.4. These results demonstrated that relative ROS/RNS contents in synthetic mixtures can be easily assessed at selected detection potentials. Beyond the interest of using small volumes in microfluidic channels, optimization of detection requires precise conditions easy to implement. These were delineated to lead in microdevices to high-performances detection of oxidative stress metabolites either from analytes or from the production of a few living cells like macrophages. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.electacta.2014.08.046

文献信息

• Oxidation of Peroxynitrite by Inorganic Radicals:  A Pulse Radiolysis Study
  作者：Sara Goldstein、Abhijit Saha、Sergei V. Lymar、Gidon Czapski

  DOI：10.1021/ja9735362

  日期：1998.6.1

  peroxynitrite ion toward a number of inorganic radicals was determined by using the pulse radiolysis technique. The rate constants for the oxidation of the ONOO- ion by CO3•-, •N3, and ClO2• radicals were determined from their decay kinetics to be (7.7 ± 1.2) × 106 (I = 0.6 M), (7.2 ± 0.9) × 108, and (3.2 ± 0.3) × 104 M-1 s-1, respectively. For the •OH radical, the rate constant of (4.8 ± 0.8) × 109 M-1

  过氧亚硝酸根离子对许多无机自由基的反应性是通过使用脉冲辐解技术确定的。CO3•-、•N3 和 ClO2• 自由基氧化 ONOO- 离子的速率常数由它们的衰变动力学确定为 (7.7 ± 1.2) × 106 (I = 0.6 M), (7.2 ± 0.9) × 108 和 (3.2 ± 0.3) × 104 M-1 s-1。对于•OH 自由基，通过使用竞争动力学分析获得(4.8 ± 0.8) × 109 M-1 s-1 的速率常数。根据动力学数据估计 ONOO- 离子的氧化电位为 0.8 V。尽管在热力学上有利，但未观察到 •NO2 自由基对 ONOO- 的氧化。该反应的上限为 2.5 × 104 M-1 s-1。讨论了这些反应中的一些对在 CO2 存在和不存在下过氧亚硝酸盐分解的贡献。
• A matrix-isolation-infrared spectroscopic study of the reactions of nitric oxide with oxygen and ozone
  作者：Subhash C. Bhatia、John H. Hall

  DOI：10.1021/j100461a024

  日期：1980.11