1-Nitroso-3,5-dimethyladamantane | 1262583-10-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Nitroso-3,5-dimethyladamantane
• 英文别名: 1,3-dimethyl-5-nitrosoadamantane
• CAS: 1262583-10-7
• 化学式: C₁₂H₁₉NO
• 分子量: 193.28
• InChiKey: POHXMTWSWALMTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS<br/>[FR] PROMÉDICAMENTS D'INHIBITEURS DE GCPII À BASE D'HYDROXAMATE
  申请人：UNIV JOHNS HOPKINS

  公开号：WO2018094334A1

  公开（公告）日：2018-05-24

  Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed.

  本发明揭示了羟肟基GCPII抑制剂的前药及其用于治疗疾病或病况的方法。
• Prodrug compositions and utility of hydroxamate-based GCPII inhibitors
  申请人：The Johns Hopkins University

  公开号：US11059775B2

  公开（公告）日：2021-07-13

  Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed.

  本发明公开了羟基氨基甲酸酯类 GCPII 抑制剂的原药及其用于治疗疾病或病症的方法。
• ADAMANTANE MODULATORS OF NMDA RECEPTOR AND/OR 5HT3 RECEPTOR
  申请人：Gant Thomas G.

  公开号：US20100130528A1

  公开（公告）日：2010-05-27

  The present invention relates to new adamantane modulators of NMDA receptors and/or 5HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
• NOVEL PRODRUG COMPOSITIONS AND UTILITY OF HYDROXAMATE-BASED GCPII INHIBITORS
  申请人：The Johns Hopkins University

  公开号：US20190352255A1

  公开（公告）日：2019-11-21

  Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed.
• PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS
  申请人：The Johns Hopkins University

  公开号：US20210355079A1

  公开（公告）日：2021-11-18

  Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed.