申请人:NISSAN CHEMICAL INDUSTRIES, LTD.
公开号:US20160129119A1
公开(公告)日:2016-05-12
An object is to provide dispersion containing lipid peptide type compound useful as low molecular weight gelator, such as lipid dipeptide and lipid tripeptide, and dissolution accelerator capable of dissolving the lipid peptide type compound at lower temperature and more easily. It is also an object to provide dispersion that can form hydrogel by simpler method and under milder condition (low temperature) and from which gel can be obtained as gel having high thermal stability, and provide method for forming the gel. Dispersion including: a lipid peptide type compound in which peptide portion formed by repetition of at least two or more identical or different amino acids is bonded to lipid portion including C
10-24
aliphatic group; dissolution accelerator having, in molecules thereof, hydrophilic portion and hydrophobic portion, the hydrophilic portion having betaine structure; and water; and method for producing hydrogel by use of the dispersion.
本发明旨在提供一种包含脂肽类化合物的分散体,该化合物可用作低分子量凝胶剂,例如脂肽二肽和脂肽三肽,并且提供一种溶解加速剂,该加速剂能够在较低温度和更容易地溶解脂肽类化合物。本发明还旨在提供一种能够通过更简单的方法在较温和的条件下(低温)形成水凝胶的分散体,并从中可以得到具有高热稳定性的凝胶,并提供形成凝胶的方法。包括以下成分的分散体:脂肽类化合物,其中由至少两个或更多相同或不同的氨基酸重复形成的肽部分与包括C10-24脂肪族基团的脂肪部分相结合;溶解加速剂,其分子中具有亲水部分和疏水部分,亲水部分具有甜菜碱结构;和水;以及利用该分散体制备水凝胶的方法。