isovanillin propylene glycol acetal | 1412860-11-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: isovanillin propylene glycol acetal
• 英文别名: 2-Methoxy-5-(4-methyl-1,3-dioxolan-2-yl)phenol；2-methoxy-5-(4-methyl-1,3-dioxolan-2-yl)phenol
• CAS: 1412860-11-7
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: BAINFEAVHCQLBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  异香兰素 、 1,2-丙二醇 在 FIBAN K-1 cation exchanger 作用下， 以 苯 为溶剂， 以88%的产率得到isovanillin propylene glycol acetal
  参考文献：
  名称：

  Synthesis of 1,3-dioxolanes from substituted benzaldehydes of the vanillin series

  摘要：

  Condensation of substituted benzaldehydes of the vanillin series with propane-1,2-diol and 3-chloropropane-1,2-diol in boiling benzene in the presence of FIBAN K-1 sulfonated cation exchanger as catalyst gave the corresponding substituted 1,3-dioxolanes.

  DOI：

  10.1134/s1070363212090149

文献信息

• METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20180057447A1

  公开（公告）日：2018-03-01

  The purpose of the present invention is to provide a cooling agent composition containing a novel methyl menthol derivative having no undesirable feeling of stimulation, malodor, bitterness, or the like, it being possible to use the cooling agent composition as a cooling agent or sensory stimulation agent having exceptional persistence of a sense of coolness and refreshing feeling. The present invention pertains to a cooling agent composition containing a methyl menthol derivative represented by general formula (1A) or general formula (1B).

  本发明的目的是提供一种冷却剂组合物，其中包含一种新型的甲基薄荷醇衍生物，不具有刺激感、恶臭、苦味等不良感觉，可以将该冷却剂组合物用作具有出色持久感觉的凉爽和清新感的冷却剂或感官刺激剂。本发明涉及一种含有由通式（1A）或通式（1B）表示的甲基薄荷醇衍生物的冷却剂组合物。
• COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20200297607A1

  公开（公告）日：2020-09-24

  A cooling agent composition contains a 2,2,6-trimethylcyclohexanecarboxylic acid derivative represented by the following general formula (1). The symbol * represents an asymmetric carbon atom. X represents NH, N(ZAr 2 ), O or S, Z represents a single bond or an alkylene group having 1 to 3 carbon atoms which may have a substituent, Ar 2 represents an aryl group having 6 to 20 carbon atoms which may have a substituent or an aromatic heterocyclic group having 2 to 15 carbon atoms which may have a substituent. Y each independently represents a methylene group which may have a substituent, and n represents an integer of 0 to 3. Ar 1 represents an aryl group having 6 to 20 carbon atoms which may have a substituent or an aromatic heterocyclic group having 2 to 15 carbon atoms which may have a substituent.

  一个制冷剂组合物包含一个由以下通用式（1）表示的2,2,6-三甲基环己烷羧酸衍生物。符号*代表一个不对称碳原子。X代表NH，N(ZAr2)，O或S，Z代表一个单键或一个具有1到3个碳原子的烷基基团，可以有一个取代基，Ar2代表一个具有6到20个碳原子的芳基基团，可以有一个取代基或一个具有2到15个碳原子的芳香杂环基团，可以有一个取代基。Y各自独立地表示一个可以有取代基的亚甲基基团，n表示0到3的整数。Ar1代表一个具有6到20个碳原子的芳基基团，可以有一个取代基或一个具有2到15个碳原子的芳香杂环基团，可以有一个取代基。
• FLAVOR-IMPROVING AGENT
  申请人：Takasago International Corporation

  公开号：EP3225115A1

  公开（公告）日：2017-10-04

  The present invention provides a flavor-improving agent comprising an extract from a plant of the genus Quercus of the family Fagaceae, wherein the ratio of whisky lactone content to total polyphenol content is 0.2% or higher; and a method for the manufacture thereof.

  本发明提供了一种风味改进剂，它由一种栎科栎属植物的提取物组成，其中威士忌内酯含量与总多酚含量之比为 0.2% 或更高；本发明还提供了一种制造方法。
• Methyl menthol derivative and cooling agent composition containing same
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US10494330B2

  公开（公告）日：2019-12-03

  The purpose of the present invention is to provide a cooling agent composition containing a novel methyl menthol derivative having no undesirable feeling of stimulation, malodor, bitterness, or the like, it being possible to use the cooling agent composition as a cooling agent or sensory stimulation agent having exceptional persistence of a sense of coolness and refreshing feeling. The present invention pertains to a cooling agent composition containing a methyl menthol derivative represented by general formula (1A) or general formula (1B).

  本发明的目的是提供一种含有新型甲基薄荷醇衍生物的清凉剂组合物，这种清凉剂组合物没有刺激、恶臭、苦味等不良感觉，可以用作清凉剂或感官刺激剂，具有特别持久的清凉感和清爽感。本发明涉及一种含有通式（1A）或通式（1B）所代表的甲基薄荷醇衍生物的清凉剂组合物。
• Methylmenthol derivative and cool-sensation imparter composition containing same
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US11236042B2

  公开（公告）日：2022-02-01

  A cooling agent composition includes a methyl menthol derivative represented by the following general formula (1). In the formula (1), a symbol * indicates an asymmetric carbon atom, X represents a hydrogen atom or a substituent, and Y represents an aryl group having 6 to 20 carbon atoms which may have a substituent.

  一种冷却剂组合物包括由以下通式(1)表示的甲基薄荷醇衍生物。在式（1）中，符号 * 表示不对称碳原子，X 表示氢原子或取代基，Y 表示具有 6 至 20 个碳原子的芳基，该芳基可能具有取代基。