N,N-dipropyl-β-alanine | 57724-25-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dipropyl-β-alanine
• 英文别名: N,N-Dipropyl-β-alanin；β-Dipropylaminopropionsaeure；N,N-Dipropyl-β-alanin；3-(Dipropylazaniumyl)propanoate
• CAS: 57724-25-1
• 化学式: C₉H₁₉NO₂
• mdl: MFCD09704021
• 分子量: 173.255
• InChiKey: OMEAIFQIIGBCPE-UHFFFAOYSA-N

物化性质

• 熔点：
  87-88 °C
• 沸点：
  263.0±23.0 °C(Predicted)
• 密度：
  0.968±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N,N-Dipropyl-β-alanin-(trimethylsilylester) 在 盐酸 作用下， 以 乙醚 为溶剂， 生成 N,N-dipropyl-β-alanine
  参考文献：
  名称：

  Reactions of Group IV Organometallic Compounds. I. The Reaction of Trimethylsilyldialkylamines with β-Propiolactone

  摘要：

  DOI：

  10.1021/jo01350a015

文献信息

• WRINKLE-IMPROVING AGENT
  申请人：Shiseido Company, Limited

  公开号：EP1941861A1

  公开（公告）日：2008-07-09

  The invention provides a novel wrinkle-improving agent that has an effect of improving wrinkles, that does not entail problems of safety or pain even when applied to the skin, and that contains a very safe substance as an active component. A discovery was made that N-benzoyl-β-alanine, other specific β-alanine derivatives, and salts thereof have a wrinkle-improving effect, whereby a wrinkle-improving agent containing as an active component one, two, or more types of compounds selected from the group composed of these specific β-alanine derivatives and the salts thereof was developed.

  该发明提供了一种新型的改善皱纹的剂，具有改善皱纹的效果，即使应用于皮肤也不会带来安全或疼痛问题，并且包含一种非常安全的物质作为活性成分。发现N-苯甲酰-β-丙氨酸、其他特定的β-丙氨酸衍生物及其盐具有改善皱纹的效果，因此开发了一种改善皱纹的剂，其活性成分包含从这些特定的β-丙氨酸衍生物及其盐组成的群体中选择的一种、两种或更多种化合物。
• Peptide-Based Multimeric Targeted Contrast Agents
  申请人：Zhang Zhaoda

  公开号：US20070185311A1

  公开（公告）日：2007-08-09

  Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.

  本文描述了肽和肽靶向多聚对比剂，以及制备和使用对比剂的方法。
• Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin
  申请人：Kaminuma Mikiko

  公开号：US20120232111A1

  公开（公告）日：2012-09-13

  The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin—inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and further provides an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent comprises one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof. The external composition for skin comprises the one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent.

  本发明提供了一种角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂，具有诸如角化过度抑制、毛孔收缩或粗糙肌肤抑制/减轻等功能，不会引起感觉刺激等安全问题，非常安全，还提供了一种外用皮肤组成物，其中添加了具有上述功能的化合物。该角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂包括从β-丙氨酸衍生物和其盐的群组中选择的一种或多种化合物。该外用皮肤组成物包括上述β-丙氨酸衍生物和其盐中的一种或多种作为上述角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂。
• PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN
  申请人：Shiseido Company, Limited

  公开号：EP1880711A1

  公开（公告）日：2008-01-23

  The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin -inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and further provides an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent comprises one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof. The external composition for skin comprises the one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent.

  本发明提供了一种角化抑制剂、毛孔收缩剂或皮肤粗糙预防/改善剂，它具有抑制角化、收缩毛孔或皮肤粗糙抑制/改善等功能，不会造成感官刺激等安全问题，而且非常安全，并进一步提供了一种添加了具有上述功能的化合物的皮肤外用组合物。角化抑制剂、毛孔收缩剂或皮肤粗糙预防/改善剂包括一种或多种选自 β-丙氨酸衍生物及其盐类的化合物。皮肤外用组合物包括选自由 β-丙氨酸衍生物及其盐组成的组的一种或多种化合物，作为上述角化病抑制剂、毛孔收缩剂或皮肤粗糙预防/改善剂。
• COREATANT-INCLUDING ELECTROCHEMILUMINESCENT COMPOUNDS, METHODS, SYSTEMS AND KITS UTILIZING SAME
  申请人：——

  公开号：US20010003647A1

  公开（公告）日：2001-06-14

  A method of generating a electrochemiluminescent emission, which comprises exposing an electrochemiluminescent label linked to a coreactant, to conditions suitable for inducing electrochemiluminescence; said compound; a system for generating an electrochemiluminescent emission, which comprises said compound, means for exposing said compound to electrochemical energy, and means for detecting or measuring luminescence emitted from said compound or a composition containing same; and a kit for performing an assay using said compound.

  一种产生电致发光的方法，包括将与核心反应物相连的电致发光标记暴露于适合诱导电致发光的条件下；所述化合物；一种产生电致发光的系统，包括所述化合物、将所述化合物暴露于电化学能量的装置，以及检测或测量从所述化合物或含有该化合物的组合物发出的发光的装置；以及一种使用所述化合物进行检测的试剂盒。