N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide | 916066-98-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide
• 英文别名: N,N-dihexyl-2-methyl-1,3-benzothiazole-6-sulfonamide
• CAS: 916066-98-3
• 化学式: C₂₀H₃₂N₂O₂S₂
• 分子量: 396.618
• InChiKey: RUNSKWSFQWWYMD-UHFFFAOYSA-N

物化性质

• 沸点：
  515.9±42.0 °C(Predicted)
• 密度：
  1.123±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  26
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  86.9
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide 、 对甲苯磺酸甲酯 以 正己烷 、 乙酸乙酯 为溶剂， 以2.3 g (78%)的产率得到6-(N,N-dihexylsulfamoyl)-2,3-dimethylbenzo[d]-thiazole-3-ium tosylate
  参考文献：
  名称：

  Novel dyes for the detection or quantification of desirable target molecules

  摘要：

  本发明提供了染料、活性染料和标记试剂，可用于检测或定量理想的靶分子，如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与靶分子的结合提供信号生成。还提供了包含活性基团的染料，可用于将染料附着到将结合到理想的靶分子的探针上。本发明的新型染料已通过添加带电和极性基团进行改性，以提供有益的特性。

  公开号：

  US20060269926A1
• 作为产物：
  描述：

  二已胺 、 2-methyl-1,3-benzothiazole-6-sulfonyl chloride 以 正己烷 、 氯仿 、 乙酸乙酯 为溶剂， 以7.76 g (97%)的产率得到N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide
  参考文献：
  名称：

  Novel dyes for the detection or quantification of desirable target molecules

  摘要：

  本发明提供了染料、活性染料和标记试剂，可用于检测或定量理想的靶分子，如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与靶分子的结合提供信号生成。还提供了包含活性基团的染料，可用于将染料附着到将结合到理想的靶分子的探针上。本发明的新型染料已通过添加带电和极性基团进行改性，以提供有益的特性。

  公开号：

  US20060269926A1

文献信息

• Methods for detecting the presence, location or quantity of targets using novel dyes
  申请人：Xiang Yuejun

  公开号：US20100041020A1

  公开（公告）日：2010-02-18

  The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.

  本发明提供了染料、反应性染料和标记试剂，可用于检测或定量所需的目标分子，例如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与目标分子的结合提供信号生成。还提供了包含反应性基团的染料，可用于将染料连接到将结合到所需目标分子的探针上。本发明的新型染料已通过添加带电和极性基团进行改性，以提供有益的性质。
• Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes
  申请人：Xiang Yuejun

  公开号：US20120040430A1

  公开（公告）日：2012-02-16

  The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.

  本发明提供了染料、反应性染料和标记试剂，可用于检测或定量所需的目标分子，例如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与目标分子的结合提供信号生成。还提供了包含反应性基团的染料，可用于将染料附着到将结合到所需目标分子的探针上。本发明的新型染料已通过添加带电和极性基团进行改性，以提供有益的性质。
• Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules
  申请人：Enzo Life Sciences, Inc.

  公开号：US08153802B2

  公开（公告）日：2012-04-10

  The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.

  本发明提供了染料、反应染料和标记试剂，可用于检测或定量所需的目标分子，如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与目标分子的结合提供信号产生。还提供了包含反应基团的染料，可用于将染料附着到将结合到所需目标分子的探针上。本发明的新型染料通过添加带电和极性基团进行了改性，以提供有益的性质。
• Dyes for the detection or quantification of desirable target molecules
  申请人：Enzo Life Sciences, Inc.

  公开号：US07569695B2

  公开（公告）日：2009-08-04

  The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.

  本发明提供了染料、反应性染料和标记试剂，可用于检测或定量所需的目标分子，例如蛋白质和核酸。提供了可在溶液中自由使用的染料，其中染料与目标分子的结合提供信号生成。还提供了包含反应性基团的染料，可用于将染料附着到将结合到所需目标分子的探针上。本发明的新型染料通过添加带电和极性基团进行了改性，以提供有益的特性。
• Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules
  申请人：Xiang Yuejun

  公开号：US20130045480A1

  公开（公告）日：2013-02-21

  The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.

  本发明提供了染料、反应染料和标记试剂，可用于检测或定量所需的目标分子，如蛋白质和核酸。提供了可以在溶液中自由使用的染料，其中染料与目标分子的结合提供信号生成。还提供了包含反应性基团的染料，可用于将染料附着到将与所需的目标分子结合的探针上。本发明的新型染料已通过添加带电和极性基团进行改性，以提供有益的特性。