Polyethylenimine (Branched) (Technical Grade)

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Polyethylenimine (Branched) (Technical Grade)
• 英文别名: N'-[2-[2-[2-(2-aminoethylamino)ethyl-[2-[bis(2-aminoethyl)amino]ethyl]amino]ethyl-[2-[2-[bis(2-aminoethyl)amino]ethylamino]ethyl]amino]ethyl]ethane-1,2-diamine
• 化学式: C₂₄H₆₃N₁₃
• 分子量: 533.8
• InChiKey: WJNSGRVBTZNVQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.6
• 重原子数：
  37
• 可旋转键数：
  30
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  205
• 氢给体数：
  9
• 氢受体数：
  13

文献信息

• Methods and compounds to suppress viral genome release and packaging
  申请人：Carnegie Mellon University

  公开号：US10702572B2

  公开（公告）日：2020-07-07

  Provided herein are methods of suppressing viral nucleic acid, e.g. double-stranded (ds) DNA, genome release from or packaging of viruses having their nucleic acid genome packaged under stress in their capsid, and compositions useful for that purpose. The methods alter the ionic environment of the nucleic acid within the capsid and thereby prevent release of, and/or interfere with packaging of the viral genome.

  本文提供了抑制病毒核酸（如双链（ds）DNA）基因组从病毒中释放或包装的方法，这些病毒的核酸基因组在应力作用下被包装在其外壳中，还提供了用于此目的的组合物。这些方法可改变囊壳内核酸的离子环境，从而阻止病毒基因组的释放和/或干扰病毒基因组的包装。
• Water-Based Polyolefin Corrosion Inhibitors Based on Vinyl/Vinylidene Terminated Polyolefins
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：US20160160071A1

  公开（公告）日：2016-06-09

  A corrosion inhibitor composition useful in pipes, pilings and hulls comprising the reaction product of a vinyl/vinylidene-terminated polyolefin having at least 14 carbon atoms and a polyamine having a molecular weight of at least 500 g/mole.
• CATIONIC NANOPARTICLES FOR CO-DELIVERY OF NUCLEIC ACIDS AND THERAPEUTIC AGENTS
  申请人：THE BRIGHAM AND WOMEN'S HOSPITAL, INC.

  公开号：US20160243048A1

  公开（公告）日：2016-08-25

  Nanoparticles containing an aqueous core containing one or more nucleic acids, such as siRNA, and a shell containing one or more hydrophobic cationic materials, one or more amphiphilic materials, and one or more therapeutic, diagnostic, and/or prophylactic agents are. The hydrophobic cationic material and the hydrophobic portion of the amphiphilic material provide a non-polar polymer matrix for loading non-polar drugs, protect and promoting siRNA molecule retention inside the NP core, and control drug release. The hydrophilic portion of the amphiphilic material can form a corona around the particle which prolongs circulation of the particles in the blood stream and decreases uptake by the RES.
• Methods and Compounds to Suppress Viral Genome Release and Packaging
  申请人：Carnegie Mellon University

  公开号：US20170209524A1

  公开（公告）日：2017-07-27

  Provided herein are methods of suppressing viral nucleic acid, e.g. double-stranded (ds) DNA, genome release from or packaging of viruses having their nucleic acid genome packaged under stress in their capsid, and compositions useful for that purpose. The methods alter the ionic environment of the nucleic acid within the capsid and thereby prevent release of, and/or interfere with packaging of the viral genome.
• COMPOSITIONS CONTAINING MICROCAPSULES COATED WITH DEPOSITION PROTEINS
  申请人：International Flavors & Fragrances Inc.

  公开号：US20170189283A1

  公开（公告）日：2017-07-06

  A microcapsule composition containing microcapsules coated with a deposition protein, e.g., a protein-silanol copolymer, a protein-silane copolymer, a protein-siloxane copolymer, or a cationically modified protein, is provided as is a method for making the microcapsule composition and using the microcapsule composition in consumer products, in particular rinse-off consumer product.