methyl methylphosphonofluoridate | 353-88-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: methyl methylphosphonofluoridate
• 英文别名: O-methyl methanephosphonofluoridate；O-methyl methylphosphonofluoridate；methyl (fluoro)methylphosphonate；Methyl-methoxyphosphonofluoridat；methyl-phosphonic acid-fluoride-methyl ester；Methyl-phosphonsaeure-fluorid-methylester；Fluoro-methoxy-methylphosphonyl；Methoxymethylphosphorylfluorid；[fluoro(methyl)phosphoryl]oxymethane
• CAS: 353-88-8
• 化学式: C₂H₆FO₂P
• 分子量: 112.041
• InChiKey: LEOIIUMNVNRPNW-UHFFFAOYSA-N

物化性质

• 保留指数：
  587;586.6

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  6
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2931900090

反应信息

• 作为产物：
  描述：

  O-methyl methanephosphonothioate 在 silver fluoride 作用下， 以 氯仿 为溶剂， 以94%的产率得到methyl methylphosphonofluoridate
  参考文献：
  名称：

  通过与氟化银反应，将硫代磷酸和硒代磷酸及其衍生物轻松转化为氟化物

  摘要：

  在室温下，在CHCl 3中用氟化银水溶液处理多种硫代或硒代磷酸，可干净地形成相应的氟化物。使用其他硫代磷酸（硒代）酯（如酯，酰胺化物或卤化物）也获得了类似的结果。

  DOI：

  10.1016/s0040-4039(99)01977-2

文献信息

• Verification of the Chemical Weapons Convention: Mass Spectrometry of Alkyl Methylphosphonofluoridates
  作者：VT Borrett、RJ Mathews、ER Mattsson

  DOI：10.1071/ch9942065

  日期：——

  Under the provisions of the United Nations Chemical Weapons Convention (CWC), certain parts of chemical industry will be monitored to verify compliance with the Convention. This will include analysis of samples from industrial sites to check for the presence or absence of chemical warfare related compounds. One of the problems in screening the chemicals to be monitored under the CWC is that certain classes of chemical warfare agents are represented as families of chemicals, with many of the individual chemicals having no analytical data available. One example is the alkyl methylphosphonofluoridate family with an alkyl ester substituent from CH3 to C10H21. In this work, the mass spectra of 60 alkyl methylphosphonofluoridate family members have been studied to enable the development of rapid on-site screening methods for this family of chemicals.

  根据《联合国化学武器公约》（CWC）的规定，将对化学工业的某些部分进行监测，以核查遵守公约的情况。这包括分析工业场所的样本，检查是否存在与化学战有关的化合物。根据《化学武器公约》筛选要监测的化学品时遇到的一个问题是，某些类别的化学战剂是以化学品家族的形式出现的，其中许多单个化学品没有分析数据。其中一个例子是烷基甲基膦酰氟家族，其烷基酯取代基为 CH3 至 C10H21。在这项工作中，对 60 种烷基甲基膦酰氟家族成员的质谱进行了研究，以便为这一化学品家族开发快速的现场筛选方法。
• The use of organosilicon esters for the synthesis of alkyl phosphonofluoridates
  作者：August J. Muller

  DOI：10.1021/jo00249a046

  日期：1988.7
• Organosilicon and organophosphorus compounds with pseudohalide groups
  作者：A. A. Krolevets、V. V. Antipova、P. V. Petrovskii、I. V. Martynov

  DOI：10.1007/bf00863934

  日期：1992.1

  The reactions of alkoxydimethylsilyl cyanides with some tetracoordinated phosphorus chlorides and fluorides were investigated. It was shown that the investigated reactions are realized primarily with the replacement of two halogen atoms by functional groups. The transformations of the phosphorus acid cyanides obtained with metal fluorides were studied.
• Reddy,G.S.; Schmutzler,R., Zeitschrift fur Naturforschung. Teil B: Chemie, Biochemie, Biophysik, Biologie, 1970, vol. 25b, # 11, p. 1199 - 1214
  作者：Reddy,G.S.、Schmutzler,R.

  DOI：——

  日期：——
• Belyalov, R. U.; Kibardin, A. M.; Gazizov, T. Kh., Journal of general chemistry of the USSR, 1981, vol. 51, # 1, p. 19 - 23
  作者：Belyalov, R. U.、Kibardin, A. M.、Gazizov, T. Kh.、Pudovik, A. N.

  DOI：——

  日期：——

表征谱图