4-(diethylamino)-2-methyl-1-butene | 62751-20-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-(diethylamino)-2-methyl-1-butene
• 英文别名: 4-Diaethylamino-2-methylbuten-(1)；N,N-Diethyl-3-methylbut-3-en-1-amine
• CAS: 62751-20-6
• 化学式: C₉H₁₉N
• 分子量: 141.257
• InChiKey: HFHXFYLGPYSQIZ-UHFFFAOYSA-N

物化性质

• 沸点：
  162.4±19.0 °C(Predicted)
• 密度：
  0.788±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N,N-diethyl-3-methyl-3-butenamide 在 lithium aluminium tetrahydride 作用下， 生成 4-(diethylamino)-2-methyl-1-butene
  参考文献：
  名称：

  Dietrich,W. et al., Journal fur praktische Chemie (Leipzig 1954), 1976, vol. 318, # 6, p. 1008 - 1018

  摘要：

  DOI：

文献信息

• Reactions of Allylsilanes with Iminium Salts:  Ene Reactions with Inverse Electron Demand
  作者：Armin R. Ofial、Herbert Mayr

  DOI：10.1021/jo960516u

  日期：1996.1.1

  The N,N-dialkylmethyleneammonium hexachloroantimonates 1-SbCl6- react with allyltrimethylsilane (2a) in dichloromethane to give the alkylideneammonium ions 3 and 3' via ene reactions with inverse electron demand, where the allyltrimethylsilane (2a) behaves as enophile. Under the same conditions (2-methylallyl)trimethylsilane (2b) undergoes ordinary ene reactions with iminium ions, with the allylsilane 2b acting as the ene component. The different course of the ene reactions is explained by the varied steric strain in the pericyclic transition states 14-18. S(E)2' products, which are the main products under more nucleophilic reaction conditions, have only been detected in trace amounts.
• Chelation Assistance in the Activation of Csp3-S Bonds in Nickel-Catalyzed Cross-Coupling Reactions
  作者：Ken-Tsung Wong、Tien-Min Yuan、Maw Cherng Wang、Hsiao-Hsian Tung、Tien-Yau Luh

  DOI：10.1021/ja00099a009

  日期：1994.10

  An unprecedented chelation approach to activate C(sp)3-S bonds in nickel-catalyzed cross-coupling reactions is described. Our theme was based on the formation of a chelation complex which results in the enhancement of the reactivity of aliphatic carbon-sulfur bonds. When two dithioacetal functionalities are located in close proximity, selective olefination of one of these two dithioacetal groups can thus be achieved conveniently. Depending on the relative positions of the newly formed double bond and the remaining dithioacetal group, tandem olefination occurs to give the corresponding 1,5-bis-silyl-substituted pentadienes. Various neighboring heteroatom substituents (OR, OH, NR(2) as well as SR groups) can facilitate the olefination of a dithioacetal group. Poly(thioether) linkage afforded the corresponding degradation products via a B-sulfur elimination process. 1,3-Dimercapto- and 1,3-dithiolatopropanes furnish the cyclopropane formation under nickel-catalyzed reaction conditions. The reaction of a dihydrothiopyran with MeMgI in the presence of the nickel catalyst proceeds via a sulfur-coordinated ir-allyl complex, which can further activate the CS bond to give vinylcyclopropane.
• Reactions of allylstannanes with in situ generated immonium salts in protic solvent: a facile aminomethano destannylation process
  作者：Paul A. Grieco、Ali Bahsas

  DOI：10.1021/jo00383a048

  日期：1987.4
• GRIECO P. A.; BAHSAS A., J. ORG. CHEM., 52,(1987) N 7, 1378-1380
  作者：GRIECO P. A.、 BAHSAS A.

  DOI：——

  日期：——
• Dietrich,W. et al., Journal fur praktische Chemie (Leipzig 1954), 1976, vol. 318, # 6, p. 1008 - 1018
  作者：Dietrich,W. et al.

  DOI：——

  日期：——