1,5-Dimethoxyxanthon | 14869-88-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1,5-Dimethoxyxanthon
• 英文别名: 1,5-Dimethoxyxanthen-9-one；1,5-dimethoxyxanthen-9-one
• CAS: 14869-88-6
• 化学式: C₁₅H₁₂O₄
• 分子量: 256.258
• InChiKey: URNKYGJICFMIRI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-methoxy-2-(3-methoxyphenoxy)benzaldehyde 在 叔丁基过氧化氢 、 dichloro(p-cymene)ruthenium(II) dimer 作用下， 以 乙腈 为溶剂， 以33%的产率得到1,5-Dimethoxyxanthon
  参考文献：
  名称：

  [RuCl2(p-cymene)2]2 catalyzed cross dehydrogenative coupling (CDC) toward xanthone and fluorenone analogs through intramolecular C–H bond functionalization reaction

  摘要：

  A synthetic approach toward xanthone and fluorenone derivatives through ruthenium catalyzed intramolecular C-H bond functionalization using an external oxidant has been developed. In the presence of [RuCl2(p-cymene)(2)](2), a variety of substituted ortho-aryloxy/aryl benzaldehydes underwent cross dehydrogenative coupling to afford the corresponding analogs in moderate to good yields. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.08.062

文献信息

• [RuCl2(p-cymene)2]2 catalyzed cross dehydrogenative coupling (CDC) toward xanthone and fluorenone analogs through intramolecular C–H bond functionalization reaction
  作者：Sudipta Kumar Manna、Srinivas Lavanya Kumar Manda、Gautam Panda

  DOI：10.1016/j.tetlet.2014.08.062

  日期：2014.10

  A synthetic approach toward xanthone and fluorenone derivatives through ruthenium catalyzed intramolecular C-H bond functionalization using an external oxidant has been developed. In the presence of [RuCl2(p-cymene)(2)](2), a variety of substituted ortho-aryloxy/aryl benzaldehydes underwent cross dehydrogenative coupling to afford the corresponding analogs in moderate to good yields. (C) 2014 Elsevier Ltd. All rights reserved.