N-methyl-2-hydroxyethylammonium formate | 866569-50-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methyl-2-hydroxyethylammonium formate
• 英文别名: 2-hydroxy-N-methylethanaminium formate；2-hydroxyethyl(methyl)azanium;formate
• CAS: 866569-50-8
• 化学式: CH₂O₂*C₃H₉NO
• 分子量: 121.136
• InChiKey: NNNOZHCVOZLRIP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-甲基-2-羟基乙胺 、 甲酸 反应 24.0h， 生成 N-methyl-2-hydroxyethylammonium formate
  参考文献：
  名称：

  Hydroxyl ammonium ionic liquids as media for biocatalytic oxidations

  摘要：

  羟基铵离子液体是一种可生物降解、无毒的第三代离子液体家族，对金属蛋白如细胞色素c的催化效率具有益处。

  DOI：

  10.1039/c5gc02381e

文献信息

• Synthesis and structure-properties relationship studies of biodegradable hydroxylammonium-based protic ionic liquids
  作者：Andromachi Tzani、Marianthi Elmaloglou、Charalampos Kyriazis、Dionysia Aravopoulou、Ioannis Kleidas、Achilleas Papadopoulos、Efstathia Ioannou、Apostolos Kyritsis、Epaminondas Voutsas、Anastasia Detsi

  DOI：10.1016/j.molliq.2016.09.086

  日期：2016.12

  Abstract In this work sixteen hydroxyl ammonium Protic Ionic Liquids derived from a proton transfer reaction between four different substituted amines and four different low molecular weight aliphatic and alicyclic carboxylic acids have been synthesized. The synthesized PILs were structurally characterized by NMR and FT-IR spectroscopy whereas two of their more important physicochemical properties

  摘要 在这项工作中，合成了 16 种羟基铵质子离子液体，这些质子离子液体源自四种不同的取代胺和四种不同的低分子量脂肪族和脂环族羧酸之间的质子转移反应。合成的 PIL 通过 NMR 和 FT-IR 光谱进行结构表征，同时评估了它们的两个更重要的物理化学性质，即粘度和玻璃化转变温度 (T g )。讨论了烷基链长度和取代对 PILs 支架的阴离子和阳离子组分的影响，以研究其性质。似乎 T g 值主要受羧酸根阴离子结构的影响，而粘度主要受 PIL 的阳离子部分的结构特征控制。为了估计它们的环境影响并加强它们的“绿色”特性，还进行了生物降解研究以及毒性评估实验。合成的 PILs 可以自信地标记为绿色，因为它们对盐水虾 A. salina 的无节幼体无毒或毒性低，而根据测量生物的压力呼吸测量法，它们显示出 41-64% 的生物降解性水平。微生物的需氧量 (BOD 5 )，以便在五天内通过生物氧化降解 PIL。
• Brønsted Ionic Liquids for Sustainable Processes: Synthesis and Physical Properties
  作者：Víctor H. Álvarez、Noelia Dosil、Rebeca Gonzalez-Cabaleiro、Silvana Mattedi、Manuel Martin-Pastor、Miguel Iglesias、José M. Navaza

  DOI：10.1021/je900550v

  日期：2010.2.11

  This report describes the synthesis of ionic liquids that incorporate the N-methyl-2-hydroxyethylammonium cation with various carboxylic acid anions and the study of some of their physical properties, including self-diffusion coefficients, density, speed of sound, viscosity, and refractive index. H-1 and C-13 NMR spectra were used to characterize the chemical structure of the species in concordance with FT-IR spectra. DOSY NMR spectra was used to determine the self-diffusion coefficients of the components, which were consistent with the formation of a lamellar or micellar liquid-crystal phase in samples containing an alkyl chain in the anion species. Thermoacoustic parameters showed that anion alkyl chain has an influence on the molecular packing of these ionic liquids. In addition, the effect of temperature on the properties seems to be related to the size and the type of aliphatic chain of the ionic liquid.
• Hydroxyl ammonium ionic liquids as media for biocatalytic oxidations
  作者：Athena A. Papadopoulou、Andromachi Tzani、Dimitrios Alivertis、Maria H. Katsoura、Angeliki C. Polydera、Anastasia Detsi、Haralambos Stamatis

  DOI：10.1039/c5gc02381e

  日期：——

  Hydroxyl ammonium ionic liquids are a biodegradable, non-toxic family of third generation ionic liquids with a beneficial effect on the catalytic efficiency of metalloproteins such as cytochrome c.

  羟基铵离子液体是一种可生物降解、无毒的第三代离子液体家族，对金属蛋白如细胞色素c的催化效率具有益处。