3-Hydroxy-5-(3,5,7-trihydroxy-4-oxochromen-2-yl)cyclohexa-3,5-diene-1,2-dione | 124233-31-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3-Hydroxy-5-(3,5,7-trihydroxy-4-oxochromen-2-yl)cyclohexa-3,5-diene-1,2-dione
• CAS: 124233-31-4
• 化学式: C₁₅H₈O₈
• 分子量: 316.224
• InChiKey: ZDZCGIANJNFWNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  141
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  杨梅素 在 氧气 作用下， 以 甲醇 为溶剂， 生成 3-Hydroxy-5-(3,5,7-trihydroxy-4-oxochromen-2-yl)cyclohexa-3,5-diene-1,2-dione
  参考文献：
  名称：

  Hydroethidine as a probe for measuring superoxide formation rates during air oxidation of myricetin and quercetin

  摘要：

  In the presence of the flavonols myricetin and quercetin, oxidation of hydroethidine (HE) by superoxide yielded ethidium (E+) instead of 2-hydroxyethidium (2-OH-E+). As a known pro-oxidant, myricetin alone was also found to be able to catalyze air oxidation of HE yielding exclusively E+. The reaction is inhibited by added superoxide dismutase, suggesting that superoxide is involved in the rate limiting step of the oxidation. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.044

文献信息

• COMPOSITIONS FOR SLEEPING DISORDERS
  申请人：Chan Hsiao Chang

  公开号：US20090124627A1

  公开（公告）日：2009-05-14

  Provided herein is a method for treating, preventing, or ameliorating a disorder such as insomnia or another sleeping disorder using a composition that contains an effective amount of one or more compounds.
• US7935714B2
  申请人：——

  公开号：US7935714B2

  公开（公告）日：2011-05-03
• Hydroethidine as a probe for measuring superoxide formation rates during air oxidation of myricetin and quercetin
  作者：Yi Ling Quek、Dejian Huang

  DOI：10.1016/j.tetlet.2011.08.044

  日期：2011.10

  In the presence of the flavonols myricetin and quercetin, oxidation of hydroethidine (HE) by superoxide yielded ethidium (E+) instead of 2-hydroxyethidium (2-OH-E+). As a known pro-oxidant, myricetin alone was also found to be able to catalyze air oxidation of HE yielding exclusively E+. The reaction is inhibited by added superoxide dismutase, suggesting that superoxide is involved in the rate limiting step of the oxidation. (C) 2011 Elsevier Ltd. All rights reserved.