((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide | 95523-63-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: ((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide
• 英文别名: N-[(2-hydroxynaphthalen-1-yl)methylideneamino]-4-nitrobenzamide
• CAS: 95523-63-0
• 化学式: C₁₈H₁₃N₃O₄
• mdl: MFCD00514350
• 分子量: 335.319
• InChiKey: NKZZPWSVRAPEDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  ((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide 、 四丁基醋酸铵 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  A simple naphthalene-based colorimetric sensor selective for acetate

  摘要：

  A new naphthalene based receptor (L) has been designed and synthesized which shows a remarkable color change from colorless to pink on selective binding with acetate. The anion recognition property of the receptor via hydrogen bonding interactions is monitored by UV-vis, fluorescence, and H-1 NMR titrations. It is observed that in each case, the receptor shows a specific selectivity toward the acetate ion over other interfering anions. Thus, a significant bathochromic shift in UV-vis spectrum with a sharp pink color in 'naked-eye' makes the receptor suitable for the detection of the acetate ion. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.104
• 作为产物：
  描述：

  4-硝基苯酰肼 、 2-羟基-1-萘甲醛 以 乙醇 为溶剂， 反应 6.0h， 生成 ((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide
  参考文献：
  名称：

  钯配合物通过PyBroP介导的原位C（sp 2）-OH活化催化2-氧吲哚的区域选择性芳构化

  摘要：

  合成，结构表征并附加了ONO钳型配体的Pd（II）配合物，已成功地用作在开放环境下通过水-有机介质中原位C（sp 2）-OH活化的2-氧吲哚的选择性C-2芳基化的催化剂室温下的气氛。该催化剂可重复使用多达四个循环。有利地，本方案不需要添加任何外部氧化剂，添加剂或相转移剂。

  DOI：

  10.1016/j.jorganchem.2016.09.026

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: MVol.C2, 7.5.1, page 678 - 685
  作者：

  DOI：——

  日期：——
• Mixed Ligand Complexes Derived from Semicarbazone Schiff Base and Heterocyclic Ligands: Structure and Antimicrobial Activity
  作者：K. Ganga Rajam、Marri Pradeep Kumar、K. Jyothi Kiran、Shivaraj

  DOI：10.1134/s1070363218050274

  日期：2018.5

  A series of M(II) ternary complexes [M(L)Phen] and [M(L)Oxine], where M = Co(II), Ni(II), Cu(II), and Zn(II), L = ((2-hydroxynaphthalen-1-yl)methylene)-4-nitrobenzohydrazide, Phen = 1,10-phenanthroline and Oxine = 8-hydroxy chloroquinoline, were synthesized and characterized by UV-Vis, ESR, IR, mass spectra, and TG-DTA data. Morphology and crystallinity of the complex [Ni(L)Phen] were studied by scanning electron microscopy. The crystal systems of Cu(II) complexes were determined by powder X-ray diffraction. Biological activity of the ligand and its metal complexes has been screened against four bacterial strains.
• Sacconi, L., Gazzetta Chimica Italiana, 1953, vol. 83, p. 884 - 893
  作者：Sacconi, L.

  DOI：——

  日期：——
• Palladium complexes catalyzed regioselective arylation of 2-oxindole via in situ C(sp2)−OH activation mediated by PyBroP
  作者：A. Vignesh、Werner Kaminsky、N. Dharmaraj

  DOI：10.1016/j.jorganchem.2016.09.026

  日期：2016.12

  Pd(II) complexes appended with ONO pincer type ligand were synthesized, structurally characterized and successfully applied as catalysts for regieoselective C−2 arylation of 2-oxindole via in situ C (sp2)−OH activation in aqueous-organic media under an open atmosphere at room-temperature. This catalyst was reused up to four cycles. Favourably, the present protocol doesn't require the addition of any

  合成，结构表征并附加了ONO钳型配体的Pd（II）配合物，已成功地用作在开放环境下通过水-有机介质中原位C（sp 2）-OH活化的2-氧吲哚的选择性C-2芳基化的催化剂室温下的气氛。该催化剂可重复使用多达四个循环。有利地，本方案不需要添加任何外部氧化剂，添加剂或相转移剂。
• A simple naphthalene-based colorimetric sensor selective for acetate
  作者：Shyamaprosad Goswami、Avijit Kumar Das、Debabrata Sen、Krishnendu Aich、Hoong-Kun Fun、Ching Kheng Quah

  DOI：10.1016/j.tetlet.2012.06.104

  日期：2012.9

  A new naphthalene based receptor (L) has been designed and synthesized which shows a remarkable color change from colorless to pink on selective binding with acetate. The anion recognition property of the receptor via hydrogen bonding interactions is monitored by UV-vis, fluorescence, and H-1 NMR titrations. It is observed that in each case, the receptor shows a specific selectivity toward the acetate ion over other interfering anions. Thus, a significant bathochromic shift in UV-vis spectrum with a sharp pink color in 'naked-eye' makes the receptor suitable for the detection of the acetate ion. (C) 2012 Elsevier Ltd. All rights reserved.