2-({2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethyl}-phenyl-amino)-ethanol | 358382-03-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-({2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethyl}-phenyl-amino)-ethanol
• 英文别名: 2-[N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]anilino]ethanol
• CAS: 358382-03-3
• 化学式: C₁₄H₂₃NO₄
• 分子量: 269.341
• InChiKey: VUZIPDNLRNPCNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  62.2
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  对二硝基苯 、 2-({2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethyl}-phenyl-amino)-ethanol 在 盐酸 、 sodium nitrite 作用下， 以 水 为溶剂， 以70%的产率得到
  参考文献：
  名称：

  Colourimetric detection of Hg2+ by a chromogenic reagent based on methyl orange and open-chain polyazaoxaalkanes

  摘要：

  The receptors L-1, L-2 and L-3 containing pendant aza-oxa binding sites have been synthesised and their UV-vis spectrum studied in the presence of alkali, alkali-earth and transition metal ions in dioxane. The dye L-3 changes its colour selectively upon Hg2+ addition. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00671-2
• 作为产物：
  描述：

  N,N-二羟乙基苯胺 、 三聚乙二醇二甲烷磺酸酯 在 sodium hydride 作用下， 以 乙腈 为溶剂， 生成 2-({2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethyl}-phenyl-amino)-ethanol
  参考文献：
  名称：

  Colourimetric detection of Hg2+ by a chromogenic reagent based on methyl orange and open-chain polyazaoxaalkanes

  摘要：

  The receptors L-1, L-2 and L-3 containing pendant aza-oxa binding sites have been synthesised and their UV-vis spectrum studied in the presence of alkali, alkali-earth and transition metal ions in dioxane. The dye L-3 changes its colour selectively upon Hg2+ addition. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00671-2

文献信息

• Unprecedented cyclisations of calix[4]arenes with glycols under the Mitsunobu protocol. Part 1: A new perspective for the synthesis of calixcrowns
  作者：Viktor Csokai、Alajos Grün、István Bitter

  DOI：10.1016/s0040-4039(03)01077-3

  日期：2003.6

  Selective ring closures of p-tert-butylthiacalix[4]arene and p-tert-butylcalix[4]arene with oligoethylene glycols were performed under the Mitsunobu protocol using the DEAD/TPP system. The method opens a new perspective for the syntheses of 1,3-calixcrowns.

  的选择性环封闭件对叔丁基硫[4]芳烃和对-叔丁基杯[4]芳烃与低聚乙二醇进行使用DEAD / TPP系统的Mitsunobu方案下进行。该方法为1，3-杯冠的合成开辟了新的前景。
• Towards the Development of Colorimetric Probes to Discriminate between Isomeric Dicarboxylates
  作者：Felix Sancenón、Ramón Martínez-Máñez、Miguel Angel Miranda、Maria-Jesus Seguí、Juán Soto

  DOI：10.1002/anie.200390178

  日期：2003.2.10
• Colourimetric detection of Hg2+ by a chromogenic reagent based on methyl orange and open-chain polyazaoxaalkanes
  作者：Felix Sancenón、Ramón Martı́nez-Máñez、Juan Soto

  DOI：10.1016/s0040-4039(01)00671-2

  日期：2001.6

  The receptors L-1, L-2 and L-3 containing pendant aza-oxa binding sites have been synthesised and their UV-vis spectrum studied in the presence of alkali, alkali-earth and transition metal ions in dioxane. The dye L-3 changes its colour selectively upon Hg2+ addition. (C) 2001 Elsevier Science Ltd. All rights reserved.