2,2,5,8,8-pentamethyl-5-(trimethylsilanyloxy-methyl)-3,7-dioxa-2,8-disila-nonane | 17866-29-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2,2,5,8,8-pentamethyl-5-(trimethylsilanyloxy-methyl)-3,7-dioxa-2,8-disila-nonane
• 英文别名: 2-Methyl-1,3-bis-trimethylsilyloxy-2-(trimethylsilyloxy-methyl)-propan；2,2,5,8,8-Pentamethyl-5-(trimethylsilyloxy-methyl)-3,7-dioxa-2,8-disila-nonan；2,2-bis-trimethylsiloxymethyl-1-trimethylsiloxypropane；Tris(trimethylsiloxymethyl)ethane；trimethyl-[2-methyl-3-trimethylsilyloxy-2-(trimethylsilyloxymethyl)propoxy]silane
• CAS: 17866-29-4
• 化学式: C₁₄H₃₆O₃Si₃
• 分子量: 336.695
• InChiKey: UINYRLPVSKXPGY-UHFFFAOYSA-N

物化性质

• 沸点：
  302.9±37.0 °C(Predicted)
• 密度：
  0.872±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.55
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,2,5,8,8-pentamethyl-5-(trimethylsilanyloxy-methyl)-3,7-dioxa-2,8-disila-nonane 在 iodine pentafluoride 作用下， 以 乙腈 为溶剂， 以82%的产率得到1,1-Difluoro-4-methyl-1λ⁵-ioda-2,6,7-trioxa-bicyclo[2.2.2]octane
  参考文献：
  名称：

  Beiträge zur chemie des iodpentafluorids teil II. Iod(V)-verbindungen mit α,ω-difunktionellen alkoholaten

  摘要：

  DOI：

  10.1016/s0022-1139(00)80926-4
• 作为产物：
  描述：

  1,1,1-三(羟甲基)乙烷 、 三甲基硅烷基甲酸酯 在 [Ru(κ¹-OAc)(κ²-OAc)(κ³-1,1,1-tris(diphenylphosphinomethyl)ethane)] 作用下， 以 乙腈 为溶剂， 反应 1.0h， 以99%的产率得到2,2,5,8,8-pentamethyl-5-(trimethylsilanyloxy-methyl)-3,7-dioxa-2,8-disila-nonane
  参考文献：
  名称：

  Silylation of O–H bonds by catalytic dehydrogenative and decarboxylative coupling of alcohols with silyl formates

  摘要：

  Silylformates HCO₂SiR₃首次作为高效的硅烷化剂用于醇类，在钌分子催化剂的存在下。

  DOI：

  10.1039/c7cc05212j

文献信息

• Use of Silylated Formiates as Hydrosilane Equivalents
  申请人：Commissariat a l'Energie Atomique et aux Energies Alternatives

  公开号：US20210292345A1

  公开（公告）日：2021-09-23

  The present invention relates to a method for preparing organic compounds of formula (I) by reaction between a silylated formiate of formula (II) and an organic compound in the presence of a catalyst and optionally of an additive. The invention also relates to use of the method for preparing organic compounds of formula (I) for the preparation of reagents for fine chemistry and for heavy chemistry, as well as in the production of vitamins, pharmaceutical products, adhesives, acrylic fibres, synthetic leathers, and pesticides.

  本发明涉及一种通过在催化剂和可选添加剂的存在下，使式(I)的有机化合物与式(II)的硅烷基甲酸酯之间发生反应来制备有机化合物的方法。 该发明还涉及利用该方法制备式(I)的有机化合物，用于制备精细化学和重化学的试剂，以及在维生素、药品、粘合剂、丙烯酸纤维、合成皮革和杀虫剂的生产中的用途。
• Process for the preparation of O-silylated hydroxyl compounds and their
  申请人：Bayer Aktiengesellschaft

  公开号：US05142081A1

  公开（公告）日：1992-08-25

  This present invention relates to a process for the preparation of O-silylated aliphatic hydroxyl, compounds by the reaction of aliphatic hydroxyl compounds with triorganochlorosilanes and removal of the resulting gaseous hydrogen chloride from the reaction mixture, characterized in that the reaction is carried out in the presence of phase transfer catalysts in the absence of solvent. The invention also relates to the use of the O-silylated hydroxyl compounds obtained by this process as starting materials for the preparation of isocyanates containing ester groups by a reaction with isocyanato carboxylic acid chlorides.

  本发明涉及一种制备O-硅烷基脂肪烃羟基化合物的方法，通过将脂肪烃羟基化合物与三有机氯硅烷反应，并从反应混合物中去除产生的气态氯化氢，其特征在于在无溶剂的情况下，在相转移催化剂的存在下进行反应。本发明还涉及通过与异氰酸酯羧酸氯化物反应，使用通过该方法得到的O-硅烷基羟基化合物作为起始材料制备含酯基的异氰酸酯的用途。
• Syntheses, Derivatives, Solubility, and Interfacial Properties of 2-Methyl-2-polyfluoroalkenyloxymethyl-1,3-propanediols:  Potential Building Blocks for Syntheses of Amphiphatic Macromolecules
  作者：Bamidele A. Omotowa、Matthew R. Judd、Brendan Twamley、Jean'ne M. Shreeve

  DOI：10.1021/jo016166f

  日期：2002.3.1

  2-Hydroxymethyl-2-methyl-1,3-propanediol (A) was reacted with (Me3Si)(2)NH and toluenesulfonyl chloride (TsCl) to give mainly CH3C(CH2OSiMe3)(3) (1), and CH3C(CH2OTs)(3) (2), respectively. With allyl bromide, the products were CH3C(CH2OCH2CH=CH2)(2)(CH,OH) (3) and CH3C(CH2OCH2CH= CH2)(CH2OH)(2).H2O (4). The reactions of 4 with perfluoroalkyl iodides (RfI) were catalyzed by Cu(I)Cl to form 2-methyl-2-pol,fluoroalkenyloxymethyl-1,3-propanediols: (RfCH=CHCH2OCH2)C(Me)(CH2OH)2 [R-f = C4F9 (5), C(8)F17 (6), and (CF2CF2)(4)OCF(CF3)(2) (7)]. Reduction of 5 and 6 with hydrogen gave two new 2-methyl-2-polyfluoroalkyloxymethyl-1,3-propanediols, 8 and 9. The sodium salt of 9 was reacted with allyl bromide or acetyl chloride to form (C8F17CH2CH2CH2OCH2)C(Me)(CH2OX)(CH2OH)(2) [where X = CH2CH=CH2 (10) or C(O)CH3 (12)] and (C8F17CH2CH2CH2OCH2)C(Me)(CH2OX)2 [where X = CH2CH=CH2 (11) or C(O)CH3 (13)]. Reaction of tolenesulfonyl chloride with 7 gave the monotosylate, 14, as the sole product. With 4-trifluoromethylbenzyl bromide, the sodium salt of 4 gave (4-CF3C6H4CH2OCH2)C(Me)(CH2CH=CH2)(CH2OH)-H2O (15). The compounds were characterized by NMR (H-1, C-13, F-19, Si-29), GC-MS, and high-resolution MS or elemental analyses. LTV evidence was obtained for partitioning of 9, 12, 14, and 15 between perfluorodecalin and n-octanol. The test compounds acted as surfactants by facilitating the solubility of phenol and Si(CH CI-12)4 in perfluorodecalin. The single-crystal X-ray structure of 8 was also obtained. It crvstallized in the monoc linic space group P21/c, and unit cell dimensions were a = 24.966(2) Angstrom (alpha = 90degrees), b = 6.1371(6) Angstrom ( beta = 100.730(2)degrees), and c = 10.5669(10) Angstrom (gamma = 90degrees).
• Silylation of O–H bonds by catalytic dehydrogenative and decarboxylative coupling of alcohols with silyl formates
  作者：Clément Chauvier、Timothé Godou、Thibault Cantat

  DOI：10.1039/c7cc05212j

  日期：——

  Silylformates HCO₂SiR₃ are used for the first time as efficient silylating agents for alcohols, in the presence of a ruthenium molecular catalyst.

  Silylformates HCO₂SiR₃首次作为高效的硅烷化剂用于醇类，在钌分子催化剂的存在下。
• Beiträge zur chemie des iodpentafluorids teil II. Iod(V)-verbindungen mit α,ω-difunktionellen alkoholaten
  作者：Hermann Josef Frohn、Wolfgang Pahlmann

  DOI：10.1016/s0022-1139(00)80926-4

  日期：1984.10