2-[4-(2-ethoxyethyl)-2-methylphenoxy]-ethylamine | 105742-63-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-[4-(2-ethoxyethyl)-2-methylphenoxy]-ethylamine
• 英文别名: 2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethylamine；2-[4-(2-Ethoxyethyl)-2-methylphenoxy]ethan-1-amine；2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethanamine
• CAS: 105742-63-0
• 化学式: C₁₃H₂₁NO₂
• 分子量: 223.315
• InChiKey: GWFPFIDAVVOOAI-UHFFFAOYSA-N

物化性质

• 沸点：
  325.2±37.0 °C(Predicted)
• 密度：
  1.005±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-[4-(2-ethoxyethyl)-2-methylphenoxy]-ethylamine 、 4,5-二氯-6-甲基嘧啶 在 三乙胺 作用下， 以 乙酸乙酯 、 甲苯 为溶剂， 生成 5-chloro-4-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethylamino}-6-methylpyrimidine
  参考文献：
  名称：

  Phenoxyalkylaminopyrimidine derivatives and insecticidal and acaricidal

  摘要：

  式（I）的化合物：##STR1##（其中R.sup.1-R.sup.5是各种传统原子或基团，m为2或3，R.sup.6 l是一个可选择的取代的烷氧基烷基，烷基硫醚基，烷基氨基烷基或杂环取代的烷基基团或--CH.sub.2--CH.dbd.NOR.sup.7，其中R.sup.7是氢，烷基，烯基或芳基）具有杀虫和杀螨活性。

  公开号：

  US04845097A1

文献信息

• Phenoxyalkylamine derivative and agricultural and horticultural chemical
  申请人：Ube Industries, Ltd.

  公开号：US05380744A1

  公开（公告）日：1995-01-10

  Disclosed are a phenoxyalkylamine compound represented by the formula (I): ##STR1## wherein R.sup.1 is C.sub.1-8 alkyl group, C.sub.3-8 cycloalkyl group, a hydrogen atom, a phenyl group, or C.sub.1-4 haloalkyl group; R.sup.2 is a halogen atom, a hydrogen atom, C.sub.1-4 alkyl group, C.sub.1-4 alkoxy group or a nitro group; R.sup.1 and R.sup.2 may be linked with each other and condensed to a pyrazole ring to form a saturated 4- to 8-membered ring; R.sup.3 is C.sub.1-15 alkyl group, C.sub.3-8 cycloalkyl group, a phenyl group, C.sub.1-4 haloalkyl group, C.sub.2-8 alkoxyalkyl group, C.sub.3-6 alkenyl group, a pyridyl group, a benzyl group, C.sub.3-8 alkoxycarbonylalkyl group, a pyrazole group, or C.sub.1-4 alkoxy group; R.sup.4 is C.sub.1-4 alkyl group, a hydrogen atom or a halogen atom; R.sup.5 is C.sub.1-20 alkyl group, a hydrogen atom, C.sub.3-6 alkenyl group, a benzyl group, a phenoxy group, a halogen atom, a cyanomethyl group or --A--O--R.sup.7 where A is C.sub.1-4 alkylene group and R.sup.7 is C.sub.1-6 alkyl group, C.sub.3-6 alkenyl group, C.sub.3-6 alkynyl group or C.sub.2-5 acyl group; and R.sup.6 is a hydrogen atom, C.sub.1-4 alkyl group or a halogen atom, a process for preparing the same and a chemical for controlling noxious organisms containing the same as an effective ingredient.

  本发明涉及一种由以下式（I）表示的苯氧基烷胺化合物：其中R.sup.1是C.sub.1-8烷基，C.sub.3-8环烷基，氢原子，苯基或C.sub.1-4卤代烷基；R.sup.2是卤原子，氢原子，C.sub.1-4烷基，C.sub.1-4烷氧基或硝基；R.sup.1和R.sup.2可以彼此连接并缩合成吡唑环以形成饱和的4-至8-成员环；R.sup.3是C.sub.1-15烷基，C.sub.3-8环烷基，苯基，C.sub.1-4卤代烷基，C.sub.2-8烷氧基烷基，C.sub.3-6烯基，吡啶基，苄基，C.sub.3-8烷氧羰基烷基，吡唑基或C.sub.1-4烷氧基；R.sup.4是C.sub.1-4烷基，氢原子或卤原子；R.sup.5是C.sub.1-20烷基，氢原子，C.sub.3-6烯基，苄基，苯氧基，卤原子，氰甲基或--A--O--R.sup.7，其中A为C.sub.1-4烷基烯基，R.sup.7为C.sub.1-6烷基，C.sub.3-6烯基，C.sub.3-6炔基或C.sub.2-5酰基；R.sup.6是氢原子，C.sub.1-4烷基或卤原子，以及一种制备该化合物的方法和含有该化合物作为有效成分的用于控制有害生物的化学品。
• Process for producing substituted phenoxyethylamines and intermediates
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0357310A1

  公开（公告）日：1990-03-07

  Disclosed are a process for producing a substituted phenoxyacetaldehyde oxime of the formula: (wherein R¹, R² and R³ are as defined in the specificat­ion), which comprises allowing a substituted phenoxyacet­aldehyde dialkylacetal of the formula: (wherein R¹, R², R³, R⁴ and R⁵ are as defined in the specification) to react with hydroxylamine; a process for producing a substituted phenoxyethylamine of the formula: (wherein R¹, R² and R³ are as defined in the specificat­ion), which comprises reducing a substituted phenoxyacet­aldehyde oxime of the formula (II) with hydrogen in the presence of a Raney-nickel catalyst; and a substituted phenoxyacetaldehyde oxime of the formula: (wherein R¹, R² and R⁶ are as defined in the specificat­ion).

  本发明公开了一种生产式如下的取代苯氧基乙醛肟的工艺： 其中R¹、R²和R³如说明书中所定义）的工艺，该工艺包括允许式中的取代的苯氧基乙醛二烷基乙缩醛(其中R¹、R²、R³、R⁴和R⁵如说明书中所定义)： (其中 R¹、R²、R³、R⁴ 和 R⁵ 如说明书中所定义）与羟胺反应； 一种生产式如下的取代苯氧基乙胺的工艺 (其中 R¹、R² 和 R³ 如说明书中所定义），该工艺包括在雷尼-镍催化剂存在下用氢还原式 (II) 的取代的苯氧基乙醛肟；以及 式中的取代苯氧基乙醛肟： (其中 R¹、R² 和 R⁶ 如说明书中所定义）。
• Phenoxyalkylamine derivatives and insecticides, acaricides and fungicides
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0405808A1

  公开（公告）日：1991-01-02

  There are disclosed a phenoxyalkylamine derivative repre­sented by the formula: wherein A¹ represents an alkylene group having 2 to 5 carbon atoms, R¹ and R² each represent hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, R³, R⁴ and R⁵ each represent hydrogen atom, an alkyl group having 1 to 5 carbon atoms or a halogen atom, R⁶ represents hydrogen atom, an alkyl group having 1 to 5 carbon atoms, an alkenyl group having 3 to 5 carbon atoms or a group -A²-X-R⁷, A² represents an alkylene group having 1 to 5 carbon atoms, X represents oxygen atom or sulfur atom, R⁷ represents a lower alkyl group having 1 to 5 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a substituted or unsubstituted aralkyl group, and an insecticide, an acaricide and a fungicide for agri­culture and horticulture, which comprises a carrier and the above phenoxyalkylamine derivative repersented as the active ingredient

  本发明公开了一种苯氧基烷基胺衍生物，由式表示： 其中A¹代表具有2至5个碳原子的亚烷基，R¹和R²各自代表氢原子或具有1至5个碳原子的低级烷基，R³、R⁴和R⁵各自代表氢原子、具有1至5个碳原子的烷基或卤素原子，R⁶代表氢原子、具有1至5个碳原子的烷基、R⁷代表具有 1 至 5 个碳原子的低级烷基、具有 3 至 5 个碳原子的烯基、具有 3 至 5 个碳原子的炔基或取代或未取代的芳烷基、 以及一种用于农业和园艺业的杀虫剂、杀螨剂和杀菌剂，它包括载体和作为活性成分的上述苯氧基烷基胺衍生物
• Phenoxyalkylamine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0521409A1

  公开（公告）日：1993-01-07

  Disclosed are a novel phenoxyalkylamine compound represented by the following formula:    wherein R¹ represents a lower alkyl group or a lower haloalkyl group; R² represents hydrogen atom or a lower alkyl group; R³ represents hydrogen atom, a lower alkyl group or a halogen atom; R⁴ represents a lower alkenyl group or -A-O-R⁶ where A represents a lower alkylene group and R⁶ represents a lower alkyl group, a lower alkenyl group or a lower alkynyl group; R⁵ represents hydrogen atom, a lower alkyl group or a halogen atom, a method for preparing the same and a chemical for controlling noxious organisms which contains the same as an active ingredient.

  本发明公开了由下式表示的新型苯氧基烷基胺化合物： 其中 R¹ 代表低级烷基或低级卤代烷基；R² 代表氢原子或低级烷基；R³ 代表氢原子、低级烷基或卤素原子；R⁴ 代表低级烯基或 -A-O-R⁶ 其中 A 代表低级亚烷基，R⁶ 代表低级烷基、低级烯基或低级炔基；R⁵ 代表氢原子、低级烷基或卤素原子、 一种制备上述物质的方法，以及一种含有上述物质作为活性成分的控制有害生物的化学品。
• Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0618195A1

  公开（公告）日：1994-10-05

  Disclosed are a phenoxyalkylamine compound having insecticidal, acaricidal and fungicidal activities and being represented by the formula (I): wherein R1 is C1-8 alkyl group, C3-8 cycloalkyl group, a hydrogen atom, a phenyl group, or C1-4 haloalkyl group; R2 is a halogen atom, a hydrogen atom, C1 -4 alkyl group, C1 -4 alkoxy group or a nitro group; R1 and R2 may be linked with each other and condensed to a pyrazole ring to form a saturated 4- to 8-membered ring; R3 is C1-15 alkyl group, C3-8 cycloalkyl group, a phenyl group, C1-4 haloalkyl group, C2-8 alkoxyalkyl group, C3-6 alkenyl group, a pyridyl group, a benzyl group, C3-8 alkoxycarbonylalkyl group, a pyrazole group, or C1-4 alkoxy group; R4 is C1 -4 alkyl group, a hydrogen atom or a halogen atom; R5 is C1 -2o alkyl group, a hydrogen atom, C3-6 alkenyl group, a benzyl group, a phenoxy group, a halogen atom, a cyanomethyl group or -A-O-R7 where A is C1-4 alkylene group and R7 is C1-6 alkyl group, C3-6 alkenyl group, C3-6 alkynyl group or C2-5 acyl group; and R6 is a hydrogen atom, C1 -4 alkyl group or a halogen atom, a process for preparing the same and a chemical for controlling noxious organisms containing the same as an effective ingredient.

  本发明公开了一种具有杀虫、杀螨虫和杀真菌活性的苯氧基烷基胺化合物，由式 (I) 表示： 其中 R1 是 C1-8 烷基、C3-8 环烷基、氢原子、苯基或 C1-4 卤代烷基；R2 是卤素原子、氢原子、C1-4 烷基、C1-4 烷氧基或硝基；R1 和 R2 可相互连接并缩合成吡唑环，形成饱和的 4 至 8 元环；R3是C1-15烷基、C3-8环烷基、苯基、C1-4卤代烷基、C2-8烷氧基烷基、C3-6烯基、吡啶基、苄基、C3-8烷氧基羰基、吡唑基或C1-4烷氧基；R4 是 C1-4 烷基、氢原子或卤素原子； R5 是 C1-2o 烷基、氢原子、C3-6 烯基、苄基、苯氧基、卤素原子、氰甲基或 -A-O-R7 其中 A 是 C1-4 亚烷基，R7 是 C1-6 烷基、C3-6 烯基、C3-6 炔基或 C2-5 丙烯酸基；和 R6 是氢原子、C1-4 烷基或卤素原子，以及制备上述物质的工艺和含有上述物质作为有效成分的控制有害生物的化学品。