Pyrido<3,2-f>-1,7-phenanthrolin | 217-81-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: Pyrido<3,2-f>-1,7-phenanthrolin
• 英文别名: pyrido[3,2-f][1,7]phenanthroline；Pyrido[3,2-f][1,7]phenanthrolin；Pyrido[3,2-f][1,7]phenanthroline；pyrido[2,3-f][1,10]phenanthroline
• CAS: 217-81-2
• 化学式: C₁₅H₉N₃
• 分子量: 231.257
• InChiKey: ZYKDOZFGHIXSDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,5-降冰片二烯 、 [1,2,4]Triazino[5,6-f]-1,10-phenanthroline 以 various solvent(s) 为溶剂， 反应 24.0h， 以55%的产率得到Pyrido<3,2-f>-1,7-phenanthrolin
  参考文献：
  名称：

  The new and simple ‘LEGO’ system: Its application for the synthesis of 6-oligopyridyl-1,5,12-triazatriphenylenes

  摘要：

  The condensation of 1,10-phenanthroline-5,6-dione 1 with amidrazones 2 leads to 6-hetaryl-substituted 1,2,4,8,9-pentaazatriphenylenes 3. These condensed 1,2,4-triazines can be easily transformed to pyridines by [4+2] cycloaddition with norborna-2,5-diene followed by [4+2] cycloreversions of nitrogen and cyclopentadiene. This reaction sequence offers a new, simple and general access to 6-oligopyridyl-1,5, 1 2-triazatriphenylenes 4. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02044-9

文献信息

• METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE
  申请人：MCFARLAND Sherri Ann

  公开号：US20160039854A1

  公开（公告）日：2016-02-11

  Compositions of the invention include metal-based coordination complexes, which are preferably tunable photodynamic compounds. The compositions and complexes are useful as therapeutic agents and as in vivo diagnostic agents for treating or preventing diseases including those that involve hyperproliferating cells in their etiology, such as cancer. Compositions and complexes of the invention are further capable of destroying microbial cells, such as bacteria, fungi, and protozoa, and destroying viruses. The compositions and complexes are also capable of modulating cell function in other ways.
• The new and simple ‘LEGO’ system: Its application for the synthesis of 6-oligopyridyl-1,5,12-triazatriphenylenes
  作者：Gunther R. Pabst、Oliver C. Pfu¨ller、Ju¨rgen Sauer

  DOI：10.1016/s0040-4039(98)02044-9

  日期：1998.11

  The condensation of 1,10-phenanthroline-5,6-dione 1 with amidrazones 2 leads to 6-hetaryl-substituted 1,2,4,8,9-pentaazatriphenylenes 3. These condensed 1,2,4-triazines can be easily transformed to pyridines by [4+2] cycloaddition with norborna-2,5-diene followed by [4+2] cycloreversions of nitrogen and cyclopentadiene. This reaction sequence offers a new, simple and general access to 6-oligopyridyl-1,5, 1 2-triazatriphenylenes 4. (C) 1998 Elsevier Science Ltd. All rights reserved.