2-methyl cyclohexanone semicarbazone | 4549-20-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-methyl cyclohexanone semicarbazone
• 英文别名: 2-Methyl-cyclohexanon-semicarbazon；2-(2-methylcyclohexylidene)-hydrazinecarboxamide；[(2-methylcyclohexylidene)amino]urea
• CAS: 4549-20-6
• 化学式: C₈H₁₅N₃O
• mdl: MFCD07280981
• 分子量: 169.227
• InChiKey: ZOMWHULATAXVJE-UHFFFAOYSA-N

物化性质

• 熔点：
  188-189.5 °C
• 密度：
  1.24±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  67.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2928000090

反应信息

• 作为反应物：
  描述：

  2-methyl cyclohexanone semicarbazone 在 potassium permanganate 、 silica gel 作用下， 以 水 为溶剂， 反应 0.75h， 以82%的产率得到2-甲基环己酮
  参考文献：
  名称：

  Wet Silica-Supported Permanganate for the Cleavage of Semicarbazones and Phenylhydrazones under Solvent-Free Conditions

  摘要：

  Wet silica-supported potassium permanganate was used as an inexpensive and efficient reagent for conversion of semicarbazones and phenylhydrazones to the corresponding carbonyl compounds under solid-state conditions.

  DOI：

  10.1021/jo034217y
• 作为产物：
  描述：

  2-氯环己酮 生成 2-methyl cyclohexanone semicarbazone
  参考文献：
  名称：

  Cis- and Trans-Chlorohydrins of Δ¹-Methylcyclohexene¹

  摘要：

  DOI：

  10.1021/ja01324a046

文献信息

• Union presence and executive compensation: An exploratory study
  作者：Parbudyal Singh、Naresh C. Agarwal

  DOI：10.1007/s12122-002-1032-4

  日期：2002.12

  While executive compensation has historically attracted considerable attention and controversy, this issue is becoming increasingly more contentious as organizations attempt to cut labor costs through reengineering and downsizing. Unions, governments, and workers are becoming critical of seemingly excessive executive compensation while employees are asked to make concessions. In fact, many labor organizations are specif-ically targeting executive compensation for criticisms: Witness their web sites tracking executive pay and numerous press releases and public statements. However, do unions, through their presence in a firm, affect executive compensation? While there is con-siderable research on the determinants and correlates of executive compensation, the literature is silent on the role of unions. We investigate the distinctive effects of union presence with data on a sample of Canadianbased metalmining firms. The differences between union and nonunion firms, as well as the unique effects of union presence, are analyzed and future research suggested.

  虽然高管薪酬历史上一直备受关注和争议，但随着组织通过重组和裁员试图降低劳动成本，这一问题变得愈发激烈。工会、政府和工人对看似过高的高管薪酬表示批评，而员工却被要求做出让步。事实上，许多工会组织正专门针对高管薪酬提出批评：请查看他们追踪高管薪酬的网站以及众多的新闻稿和公开声明。然而，工会在公司内的存在是否会影响高管薪酬？尽管有大量关于高管薪酬决定因素和相关性的研究，但文献中对工会角色的探讨却寂寂无声。我们利用加拿大的一些金属矿业公司数据，研究工会存在的独特影响。分析了有工会和无工会公司的差异，以及工会存在的独特效应，并提出了未来的研究建议。
• 77Se and15N NMR investigation of some cycloalkeno-1,2,3-selenadiazole derivatives
  作者：Helmut Duddeck、Petra Wagner、Dieter Müller、Joseph Csaba Jászberényi

  DOI：10.1002/mrc.1260280614

  日期：1990.6

  The 13C, 15N and 77Se NMR data (chemical shifts and coupling constants) of some cycloakeno‐1,2,3‐selenadiazoles are presented. Extremely large 77Se chemical shifts are found. 15N, 77Se coupling constants, obtained at natural abundance, are reported for the first time. Strong signal shifts due to different sizes of the cycloakeno rings can be qualitatively rationalized in terms of electron transfer

  提供了一些环烯基-1,2,3-硒二唑的 13C、15N 和 77Se NMR 数据（化学位移和耦合常数）。发现了非常大的 77Se 化学位移。首次报道了在自然丰度下获得的 15N、77Se 耦合常数。就氮原子和硒原子之间的电子转移而言，可以定性地合理化由于不同大小的环烯基环而导致的强信号偏移。在 4-甲基-4,5,6,7-四氢苯并-1,2,3-硒二唑中发现了甲基对 N-3 的正 γ-syn 效应。
• Interrupted Dance of Five Heteroatoms: Reinventing Ozonolysis to Make Geminal Alkoxyhydroperoxides from C═N Bonds
  作者：Ivan A. Yaremenko、Dmitri I. Fomenkov、Roman A. Budekhin、Peter S. Radulov、Michael G. Medvedev、Nikolai V. Krivoshchapov、Liang-Nian He、Igor V. Alabugin、Alexander O. Terent’ev

  DOI：10.1021/acs.joc.4c00233

  日期：2024.4.19

  Four heteroatoms dance in the cascade of four pericyclic reactions initiated by ozonolysis of C═N bonds. Switching from imines to semicarbazones introduces the fifth heteroatom that slows this dance, delays reaching the thermodynamically favorable escape path, and allows efficient interception of carbonyl oxides (Criegee intermediates, CIs) by an external nucleophile. The new three-component reaction

  四个杂原子在由 C=N 键臭氧分解引发的四个周环反应的级联中起舞。从亚胺切换到缩氨基脲引入了第五个杂原子，它减缓了这种舞蹈，延迟了到达热力学上有利的逃逸路径，并允许外部亲核试剂有效拦截羰基氧化物（Criegee中间体，CI）。醇、臭氧和肟/缩氨基脲的新型三组分反应极大地促进了单过氧缩醛（烷氧基氢过氧化物）的合成。
• Dimroth; Resin; Zetzsch, Chemische Berichte, 1940, vol. 73, p. 1399,1404
  作者：Dimroth、Resin、Zetzsch

  DOI：——

  日期：——
• Vavon; Berton, Bulletin de la Societe Chimique de France, 1925, vol. <4> 37, p. 297,298
  作者：Vavon、Berton

  DOI：——

  日期：——