The present invention provides sterols and uses thereof to treat vision disorders. In one embodiment, composition comprising pharmaceutically effective amount of lanosterol is used to treat and/or prevent vision disorders in a subject. In another embodiment, composition comprising pharmaceutically effective amount of lanosterol is used to treat cataract or blindness/impaired vision in a subject. In yet another embodiment, composition comprising lanosterol is used to dissolve amyloid-like fibrils of crystallin proteins.
本发明提供了用于治疗视力障碍的
甾醇及其用途。在一个实施方案中,包含药学有效量
羊毛甾醇的组合物用于治疗和/或预防受试者的视力障碍。在另一个实施方案中,包含药学有效量
羊毛甾醇的组合物用于治疗受试者的白内障或失明/视力受损。在另一个实施方案中,包含
羊毛甾醇的组合物用于溶解晶体蛋白的淀粉样纤维。