1-Methyl-9H-xanthene | 77680-69-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1-Methyl-9H-xanthene
• CAS: 77680-69-4
• 化学式: C₁₄H₁₂O
• 分子量: 196.24
• InChiKey: WWIKWOJUJQCHIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] COUMARIN COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND PROCESS FOR PREPARING THE SAME<br/>[FR] COMPOSÉS À BASE DE COUMARINE POUR LE TRAITEMENT DE MALADIES CARDIOVASCULAIRES ET LEUR PROCÉDÉ DE PRÉPARATION
  申请人：DELHI UNIVERSITY

  公开号：WO2009157020A1

  公开（公告）日：2009-12-30

  The present invention relates to compounds of Formula (I): wherein- X and Y represent O, S, NR'; Rn represents alkyl, aryl, OR1, NH2, SR1, NR1R2. wherein R1, R2 = H, alkyl, phenyl, aryl, OCOR3, SCOR3, NHCOR3, NR1COR3, etc. (wherein R3 represents alkyl, phenyl, aryl, heteroaryl); R' and R" represent H, alkyl, phenyl, substituted phenyl, phenyloxy, substituted phenyloxy, amino, monosubstitutedamino, disubstitutedamino, aryl, heteroaryl, aryloxy, heteroaryloxy, alkoxy, thioalkyl, thioalkyloxy, halo and a process for preparing the same.

  本发明涉及公式（I）的化合物：其中- X和Y代表O，S，NR'; Rn代表烷基，芳基，OR1，NH2，SR1，NR1R2。其中R1，R2 = H，烷基，苯基，芳基，OCOR3，SCOR3，NHCOR3，NR1COR3等（其中R3代表烷基，苯基，芳基，杂芳基）; R'和R"代表H，烷基，苯基，取代苯基，苯氧基，取代苯氧基，氨基，单取代氨基，双取代氨基，芳基，杂芳基，芳氧基，杂芳氧基，烷氧基，硫代烷基，硫代烷氧基，卤素等，以及制备它们的过程。
• [EN] SULFOXIMINE COMPOUND AND USE THEREOF<br/>[FR] COMPOSÉ SULFOXIMINE ET SON UTILISATION<br/>[ZH] 亚磺酰亚胺类化合物及其应用
  申请人：MEDSHINE DISCOVERY INC

  公开号：WO2022268119A1

  公开（公告）日：2022-12-29

  涉及亚磺酰亚胺类化合物及其应用，具体公开了下式化合物或其药学上可接受的盐。
• Volume boosting molding hair coloring creme formulation
  申请人：Greene Michael V.

  公开号：US10987284B2

  公开（公告）日：2021-04-27

  An improved hair color formulation treats hair to provide volume, viscosity, color and hair follicle stimulation. The color formulation is appointed to be used in hair products, and comprises a natural color agent and at least one agent providing anti-dihydrotestosterone (DHT) effects. Hair products include styling products, cleansing products, concealment products, and dying products. In one embodiment, the formulation comprises an aqueous emulsion, at least one hydrocarbon, at least one thickening agent, at least one humectant, at least one emollient, at least one fatty acid ester, and at least one agent providing anti-dihydrotestosterone (DHT) effects, such as caffeine, and at least one color agent. Preservatives, fibers and further treatments for male/female pattern baldness may also be added to the composition. Natural colorants are added to the hair color formulation to provide temporary coloring in addition to enhanced volume, viscosity and hair follicle stimulation.

  一种经过改良的染发剂配方可为头发提供发量、粘度、颜色和毛囊刺激。该染发配方可用于发制品中，包括一种天然染发剂和至少一种具有抗二氢睾酮（DHT）功效的制剂。发制品包括定型产品、清洁产品、遮盖产品和染色产品。在一个实施方案中，配方包括水乳剂、至少一种烃、至少一种增稠剂、至少一种保湿剂、至少一种润肤剂、至少一种脂肪酸酯、至少一种具有抗二氢睾酮（DHT）功效的制剂（如咖啡因）和至少一种着色剂。组合物中还可添加防腐剂、纤维和针对男性/女性型秃发的进一步处理剂。天然着色剂被添加到染发剂配方中，除了增加发量、粘度和刺激毛囊外，还能提供临时着色效果。
• Composition and method for the treatment of respiratory desease
  申请人：——

  公开号：US20020198228A1

  公开（公告）日：2002-12-26

  A method and composition for the treatment of respiratory disease, particularly bronchial asthma, is provided. The method and composition is provided in the form of an oral medication and includes a combination of known medications so as to avoid unnecessary undesirable reactions. The treatment composition and regimen includes a pair of compatible receptor antagonists and an adrenergic bronchodilator. The pair of compatible receptor antagonists include a leukotriene receptor antagonist and a histamine H 1 ,-receptor antagonist. The adrenergic bronchodilator is a beta 2 -adrenergic bronchodilator.

  提供了一种治疗呼吸系统疾病，特别是支气管哮喘的方法和组合物。该方法和组合物以口服药物的形式提供，包括已知药物的组合，以避免不必要的不良反应。治疗组合物和治疗方案包括一对相容受体拮抗剂和一种肾上腺素能支气管扩张剂。这对相容受体拮抗剂包括白三烯受体拮抗剂和组胺 H 1 受体拮抗剂。肾上腺素能支气管扩张剂是一种 β 2 -肾上腺素能支气管扩张剂。
• COMPOSITION AND METHOD FOR THE TREATMENT OF RESPIRATORY DISEASE
  申请人：Kaura, Sita R.

  公开号：EP1383500A1

  公开（公告）日：2004-01-28