(Z)-4-methylamino-2-buten-1-ol | 53806-08-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (Z)-4-methylamino-2-buten-1-ol
• 英文别名: 1-methylamino-but-(2Z)-en-4-ol；cis-4-Methylamino-2-buten-1-ol；(Z)-4-(methylamino)but-2-en-1-ol
• CAS: 53806-08-9
• 化学式: C₅H₁₁NO
• 分子量: 101.148
• InChiKey: QGQWPRACRGTKCQ-IHWYPQMZSA-N

物化性质

• 沸点：
  176.8±28.0 °C(Predicted)
• 密度：
  0.911±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  {(η5-C5H5)(CO)2MnCPh}BCl4 、 (Z)-4-methylamino-2-buten-1-ol 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以49%的产率得到dicarbonyl-(η(5)-cyclopentadienyl)-[(4Z)-2-aza-6-hydroxy-2-methyl-1-phenyl-4-hexen-1-ylidene]-manganese(I)
  参考文献：
  名称：

  The chemistry of metallacyclic alkenylcarbene complexes

  摘要：

  Cobaltalactams 7 with alkyl substituents at the nitrogen atom are accessible by W-irradiation of CpCo(CO)(2) 6 in the presence of the appropriate vicinal aminoalkenol 8. Thus chelated (eta 3-allyl)cobaltcarbene complexes with either (endo-amino)oxo (3), (exo-amino)oxo (11), or dioxo (2) substitution at the carbene carbon atom are now available. A synthetic route to chelated (eta(2)-alkene)-carbene complexes of chromium with allylically situated hydroxy groups is also presented. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00203-x
• 作为产物：
  描述：

  (Z)-4-chloro-but-2-en-1-ol 、 甲胺 以 二氯甲烷 为溶剂， 以42%的产率得到(Z)-4-methylamino-2-buten-1-ol
  参考文献：
  名称：

  The chemistry of metallacyclic alkenylcarbene complexes

  摘要：

  Cobaltalactams 7 with alkyl substituents at the nitrogen atom are accessible by W-irradiation of CpCo(CO)(2) 6 in the presence of the appropriate vicinal aminoalkenol 8. Thus chelated (eta 3-allyl)cobaltcarbene complexes with either (endo-amino)oxo (3), (exo-amino)oxo (11), or dioxo (2) substitution at the carbene carbon atom are now available. A synthetic route to chelated (eta(2)-alkene)-carbene complexes of chromium with allylically situated hydroxy groups is also presented. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00203-x

文献信息

• Synthesis and selective silylation of ω-hydroxy functionalized (η2-alkenyl)carbene complexes of chromium(0) and tungsten(0) Part 11. The chemistry of metallacyclic alkenylcarbene complexes
  作者：Rainer Schobert、Thomas Schmalz

  DOI：10.1016/j.jorganchem.2004.02.032

  日期：2004.5

  complexes 2 exist at room temperature as mixtures of Z- and E-isomers with regard to the C–N bond. The metallacyclic complexes (OC)4WC(η2-NMeCH2CHCHCH2OH)R (4) were obtained in good yields upon photo-decarbonylation of 2. Deprotonation/silylation of the complexes (OC)4MC(η2-NMeCH2CHCHCH2OH)Me (M=Cr: 3a; M=W: 4a) with one equivalent of nBuLi/Me3SiCl gave (OC)4MC(η2-NMeCH2CHCHCH2OSiMe3)CH3 (M=Cr: 5; M=W:

  钨（0）的类型（OC）的卡宾络合物5 WC（NMeCH 2 CHCHCH 2 OH）R 2：（R =我2A ;：R =博士2B由（OC）的氨解生成）5 W¯¯与顺式-NHMeCH 2 CH = CHCH 2 OH形成的C（OMe）R 。像它们的铬同类物1一样，络合物2在室温下以Z-和E-异构体的C – N键混合物形式存在。所述metallacyclic络合物（OC）4 WC（η 2 -NMeCH 2 CHCHCH 2 OH）R（4）在2的光脱羰作用下以高收率获得。去质子化的配合物/甲硅烷基化（OC）4（ηMC 2 -NMeCH 2 CHCHCH 2 OH）Me（M =铬：3A ; M = W：图4a）与等效的一个Ñ丁基锂/ Me的3的SiCl给（OC）4 MC（η 2 -NMeCH 2 CHCHCH 2 OSiMe 3）CH 3（M =铬：5 ; M = W：6），而与两个当量ñ丁基锂/
• Reaction of transition metal carbonyls with heterocyclic systems—II
  作者：Y. Becker、A. Eisenstadt、Y. Shvo

  DOI：10.1016/s0040-4020(01)97145-5

  日期：1974.1
• The chemistry of metallacyclic alkenylcarbene complexes
  作者：Sven-Eric Eigemann、Rainer Schobert

  DOI：10.1016/s0022-328x(99)00203-x

  日期：1999.8

  Cobaltalactams 7 with alkyl substituents at the nitrogen atom are accessible by W-irradiation of CpCo(CO)(2) 6 in the presence of the appropriate vicinal aminoalkenol 8. Thus chelated (eta 3-allyl)cobaltcarbene complexes with either (endo-amino)oxo (3), (exo-amino)oxo (11), or dioxo (2) substitution at the carbene carbon atom are now available. A synthetic route to chelated (eta(2)-alkene)-carbene complexes of chromium with allylically situated hydroxy groups is also presented. (C) 1999 Elsevier Science S.A. All rights reserved.