3-(1-benzothiophen-2-yl)-5,6-dihydro-1,4,2-oxathiazine | 163269-29-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 3-(1-benzothiophen-2-yl)-5,6-dihydro-1,4,2-oxathiazine
• CAS: 163269-29-2
• 化学式: C₁₁H₉NOS₂
• 分子量: 235.331
• InChiKey: UAQMXBBRWDUWPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  75.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-(1-benzothiophen-2-yl)-5,6-dihydro-1,4,2-oxathiazine 在 溴 、 sodium hydroxide 作用下， 以 氯仿 为溶剂， 生成 3-(3-bromo-1-benzothiophen-2-yl)-5,6-dihydro-1,4,2-oxathiazine
  参考文献：
  名称：

  [EN] OXATHIAZINE AND DITHIINE OXIDES AS INHIBITORS OF SULFHYDRYL-DEPENDENT BIOMOLECULES
  [FR] OXATHIAZINE ET OXYDES DE DITHIINE COMME INHIBITEURS DE BIOMOLÉCULES DÉPENDANTES DE SULFHYDRYLE

  摘要：

  公开号：

  WO2012024083A9
• 作为产物：
  描述：

  苯并噻吩 在 正丁基锂 、 盐酸羟胺 、 三乙胺 作用下， 以 甲醇 、 乙醚 、 正己烷 为溶剂， 反应 4.5h， 生成 3-(1-benzothiophen-2-yl)-5,6-dihydro-1,4,2-oxathiazine
  参考文献：
  名称：

  [EN] OXATHIAZINE AND DITHIINE OXIDES AS INHIBITORS OF SULFHYDRYL-DEPENDENT BIOMOLECULES
  [FR] OXATHIAZINE ET OXYDES DE DITHIINE COMME INHIBITEURS DE BIOMOLÉCULES DÉPENDANTES DE SULFHYDRYLE

  摘要：

  公开号：

  WO2012024083A9

文献信息

• Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules
  申请人：Chee Gaik-Lean

  公开号：US20120142676A1

  公开（公告）日：2012-06-07

  Novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides, more particularly, novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides that target cysteine residues of biomolecules of pharmacological importance are provided as pharmaceutically useful compounds, for example, as anticancer, antiinfectious, antigastric acid secretion, antiosteoporosic, and antiinflammatory agents.

  本发明提供了二氢-1,4,2-噁嗪硫酸酯和二氢-1,4-二硫噁嗪氧化物的新衍生物，更特别地，提供了以靶向生物分子半胱氨酸残基为目标的二氢-1,4,2-噁嗪硫酸酯和二氢-1,4-二硫噁嗪氧化物的新衍生物，作为药用化合物，例如，作为抗癌、抗感染、抗胃酸分泌、抗骨质疏松和抗炎药物。
• Modified polysaccharides, method for their production and their use
  申请人：BASF SE

  公开号：EP2899213A1

  公开（公告）日：2015-07-29

  The present invention relates to a method for producing an ether modified polysaccharide, ether modified polysaccharide obtainable by said method and the use thereof. The present invention relates to a method for producing an ethylenically unsaturated polysaccharide, ethylenically unsaturated polysaccharides obtainable by said method, polymers comprising those unsaturated polysaccharides in polymerized form and the use thereof.

  本发明涉及一种生产醚改性多糖的方法、通过所述方法可获得的醚改性多糖及其用途。本发明涉及一种生产乙烯基不饱和多糖的方法、可通过所述方法获得的乙烯基不饱和多糖、由这些不饱和多糖聚合而成的聚合物及其用途。
• Ethylenically unsaturated polysaccharides, method for their production and their use
  申请人：BASF SE

  公开号：EP2899214A1

  公开（公告）日：2015-07-29

  The present invention relates to a method for producing an ethylenically unsaturated polysaccharide, ethylenically unsaturated polysaccharides obtainable by said method, polymers comprising those unsaturated polysaccharides in polymerized form and the use thereof.

  本发明涉及一种生产乙烯基不饱和多糖的方法、可通过所述方法获得的乙烯基不饱和多糖、包含这些聚合形式的不饱和多糖的聚合物及其用途。
• Compositions containing polymeric, ionic compounds comprising imidazolium groups
  申请人：Konradi Rupert

  公开号：US10016354B2

  公开（公告）日：2018-07-10

  The present invention relates to compositions containing polymeric, ionic compounds comprising imidazolium groups. In particular, it relates to the use of polymeric, ionic compounds comprising imidazolium groups in personal care compositions and/or in biocide compositions.

  本发明涉及含有咪唑基团的聚合物离子化合物的组合物。本发明尤其涉及含咪唑基团的聚合物离子化合物在个人护理组合物和/或杀菌剂组合物中的用途。
• Formulations comprising triazoles and alkoxylated amines
  申请人：Tiedink Gerardus Johannes

  公开号：US20050080089A1

  公开（公告）日：2005-04-14

  The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising fungicidal triazoles. It also relates to formulations comprising one or more fungicidal triazoles and alkoxylated amines. These formulations are useful for the protection of any living or non-living material, such as crops, plants, fruits, seeds, objects made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of fungi.

  本发明涉及使用烷氧基化胺来增强包含杀真菌三唑的杀真菌制剂的活性。本发明还涉及由一种或多种杀真菌三唑和烷氧基化胺组成的制剂。这些制剂可用于保护任何生物或非生物材料，如农作物、植物、水果、种子、木材、茅草或类似材料制成的物体、可生物降解材料和纺织品，防止其因真菌作用而变质。