N'-(2-chloro-3,3,4,4,5,5-hexafluorocyclopenten-1-yl)-N,N'-dimethylethane-1,2-diamine | 153414-20-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N'-(2-chloro-3,3,4,4,5,5-hexafluorocyclopenten-1-yl)-N,N'-dimethylethane-1,2-diamine
• CAS: 153414-20-1
• 化学式: C₉H₁₁ClF₆N₂
• 分子量: 296.643
• InChiKey: YWFCAGYARNUSIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  N'-(2-chloro-3,3,4,4,5,5-hexafluorocyclopenten-1-yl)-N,N'-dimethylethane-1,2-diamine 生成 6-Chloro-7,8,8,9,9-pentafluoro-1,4-dimethyl-1,4-diazaspiro[4.4]non-6-ene
  参考文献：
  名称：

  Nucleophilic substitution reactions of heterocyclic amines and acyclic diamines with chlorofluoro olefins and hexafluoropropylene oxide

  摘要：

  The reactions of CH3N(H)CH2CH2N(H)CH3, CH3N(H)CH2CH2CH2N(H)CH3, and the cyclic amines piperazine, N-phenylpiperazine, and N-methylpiperazine with both cyclic and acyclic 1,2-dichloroperfluoroolefins are reported. Nucleophilic attack occurs at olefinic carbon, followed, in some cases, by cyclization and beta-elimination A variety of unusual polyfluorinated tertiary amines and heterocycles are synthesized.

  DOI：

  10.1021/jo00080a028
• 作为产物：
  描述：

  1,2-二氯六氟环戊烯 、 N,N'-二甲基乙二胺 在 三乙胺 作用下， 以 苯 为溶剂， 反应 5.0h， 以30%的产率得到N'-(2-chloro-3,3,4,4,5,5-hexafluorocyclopenten-1-yl)-N,N'-dimethylethane-1,2-diamine
  参考文献：
  名称：

  Nucleophilic substitution reactions of heterocyclic amines and acyclic diamines with chlorofluoro olefins and hexafluoropropylene oxide

  摘要：

  The reactions of CH3N(H)CH2CH2N(H)CH3, CH3N(H)CH2CH2CH2N(H)CH3, and the cyclic amines piperazine, N-phenylpiperazine, and N-methylpiperazine with both cyclic and acyclic 1,2-dichloroperfluoroolefins are reported. Nucleophilic attack occurs at olefinic carbon, followed, in some cases, by cyclization and beta-elimination A variety of unusual polyfluorinated tertiary amines and heterocycles are synthesized.

  DOI：

  10.1021/jo00080a028

文献信息

• Mir Qui-Chee, Guo Cai-Yun, Kirchmeier Robert L., Shreeve Jeanne M., J. Org. Chem, 59 (1994) N 1, S 173-177
  作者：Mir Qui-Chee, Guo Cai-Yun, Kirchmeier Robert L., Shreeve Jeanne M.

  DOI：——

  日期：——