ethyl 2-methoxyethyl carbonate | 99116-09-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: ethyl 2-methoxyethyl carbonate
• 英文别名: carbonic acid ethyl ester-(2-methoxy-ethyl ester)；Kohlensaeure-aethylester-(2-methoxy-aethylester)；1-Aethoxycarbonyloxy-2-methoxy-aethan；Aethyl-(2-methoxy-aethyl)-carbonat
• CAS: 99116-09-3
• 化学式: C₆H₁₂O₄
• 分子量: 148.159
• InChiKey: VEGHPSPMDZZFMB-UHFFFAOYSA-N

物化性质

• 沸点：
  168.1±13.0 °C(Predicted)
• 密度：
  1.030±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ethyl 2-methoxyethyl carbonate 、 苯酚 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以28%的产率得到2-甲氧基乙氧基苯
  参考文献：
  名称：

  硫和氮芥子气碳酸盐类似物

  摘要：

  当氯原子被碳酸酯部分取代时，硫和氮半芥子气化合物失去其侵蚀性。研究了新型芥菜碳酸盐类似物的嵌合效应。该反应遵循一级动力学，不需要任何碱，并与 -OH、-NH 和酸性 -CH 亲核试剂一起发生。这些分子中的大多数是未经探索的，可能为制备以前不易获得的化合物提供一种新的策略。

  DOI：

  10.1002/ejoc.201200321
• 作为产物：
  描述：

  乙二醇甲醚 、 氯甲酸乙酯 生成 ethyl 2-methoxyethyl carbonate
  参考文献：
  名称：

  Drake; Carter, Journal of the American Chemical Society, 1930, vol. 52, p. 3723

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA<br/>[FR] COMPOSÉS ET MÉTHODES DE TRAITEMENT DE LA MALARIA
  申请人：BROAD INST INC

  公开号：WO2015070204A1

  公开（公告）日：2015-05-14

  Provided herein are compounds of the formula (I) : as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.

  本文提供了公式(I)的化合物：以及其药用盐，其中取代基如规范中所披露的那样。这些化合物和含有它们的药物组合物对于治疗疟疾是有用的。
• METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：Toho Titanium CO., LTD.

  公开号：EP2876118A1

  公开（公告）日：2015-05-27

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds selected from specific aromatic dicarboxylic diesters into contact with each other to effect a reaction, followed by washing, a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing, and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种选自特定芳香族二羧酸二酯的第一内部电子供体化合物相互接触以发生反应，然后进行洗涤、第二步：使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；第三步：使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS
  申请人：TOHO TITANIUM CO., LTD.

  公开号：EP2963063A1

  公开（公告）日：2016-01-06

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds excluding an aromatic dicarboxylic acid diester into contact with each other to effect a reaction, followed by washing; a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing; and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种第一内部电子供体化合物（不包括芳香族二羧酸二酯）相互接触以发生反应，然后进行洗涤；第二步，使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；以及第三步，使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS
  申请人：Toho Titanium Co., Ltd.

  公开号：EP2963062A1

  公开（公告）日：2016-01-06

  A solid catalyst component for olefin polymerization includes titanium, magnesium, a halogen, a compound represented by (R1)kC6H4-k(COOR2)(COOR3), and a compound represented by R4O-C(=O)-O-Z-OR5. The solid catalyst component is a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity.

  一种用于烯烃聚合的固体催化剂组分包括钛、镁、卤素、由(R1)kC6H4-k(COOR2)(COOR3)代表的化合物和由R4O-C(=O)-O-Z-OR5代表的化合物。该固体催化剂组分是一种用于烯烃聚合的新型固体催化剂组分，可在聚合过程中获得优异的烯烃聚合活性和相对于氢的活性，并可生产出具有高 MFR、高立体规整度和优异刚性的烯烃聚合物。
• SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFINS, METHOD FOR PRODUCING SAME, CATALYST FOR USE IN POLYMERIZATION OF OLEFINS, AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：Toho Titanium Co., Ltd.

  公开号：EP3098243A1

  公开（公告）日：2016-11-30

  High stereoregularity, highly active catalytic performance, and good hydrogen response can be obtained by homopolymerizing propylene in the presence of a catalyst that includes a solid catalyst component including titanium, magnesium, a halogen, a carbonate compound represented by the following formula, and a diether compound. Excellent polymerization behavior can also be obtained when effecting random copolymerization or block copolymerization.         R1-O-C(=O)-O-Z-O-R2     (1) wherein R1 and R2 are a hydrocarbon group or a substituted hydrocarbon group having 1 to 24 carbon atoms, or a heteroatom-containing group, provided that R1 and R2 are either identical or different, and Z is a linking group that links two oxygen atoms through a carbon atom or a carbon chain.

  在催化剂（包括钛、镁、卤素、由下式表示的碳酸盐化合物和二醚化合物组成的固体催化剂组分）存在下均聚丙烯，可获得高立体规整度、高活性催化性能和良好的氢响应。在进行无规共聚或嵌段共聚时，也可获得优异的聚合性能。 r1-o-c(=o)-o-z-o-r2 (1) 其中，R1 和 R2 是具有 1 至 24 个碳原子的烃基或取代烃基，或含杂原子的基团，但 R1 和 R2 可以相同或不同；Z 是通过碳原子或碳链连接两个氧原子的连接基团。