[4,5-dihydroxy-2-[[(1S,3R,6S,11S,14S,16R)-14-hydroxy-15-[(5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-9-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-oxapentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-yl]oxy]oxan-3-yl] acetate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [4,5-dihydroxy-2-[[(1S,3R,6S,11S,14S,16R)-14-hydroxy-15-[(5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-9-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-oxapentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-yl]oxy]oxan-3-yl] acetate
• 化学式: C₄₂H₆₈O₁₆
• 分子量: 829.0
• InChiKey: FPMKTOHSPZKRET-ZTXGWKAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  58
• 可旋转键数：
  9
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  247
• 氢给体数：
  8
• 氢受体数：
  16

文献信息

• Antiviral Compositions And Methods Of Using The Same
  申请人：Kim Joseph Jong

  公开号：US20070259844A1

  公开（公告）日：2007-11-08

  Pharmaceutical compositions for and methods of preventing infection or treating an individual who has been identified as being infected with a Flavivirus, Pestivirus, picornovirus or coronavirus such as HCV, GB virus B, JEV, WNV, CSFV, BDV, BVDV, poliovirus, FMDV, or EMCV, comprising administering to the individual a therapeutically effective amount of one or more glucocorticoid receptor antagonist compounds, wherein said compound has steroidal structure are disclosed.
• Compositions for and Methods for Treating Hiv
  申请人：Kim Joseph Jong

  公开号：US20070259014A1

  公开（公告）日：2007-11-08

  Pharmaceutical composition comprising compounds and/or compositions useful to inhibit HIV replication are disclosed. Methods of treating individuals infected with HIV are disclosed. Methods of preventing HIV infection in high risk individuals are disclosed.
• METHODS FOR TREATING VIRAL INFECTION WITH ORAL OR INJECTIBEL DRUG SOLUTION
  申请人：Kim Jong Joseph

  公开号：US20090074721A1

  公开（公告）日：2009-03-19

  Pharmaceutical composition comprising compounds and/or compositions useful to inhibit viral replication are disclosed.