申请人:Cheng Jianjun
公开号:US20130274226A1
公开(公告)日:2013-10-17
The invention provide a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to silicon or oxygen atoms in the matrix, the organic agents are conjugated to the matrix through linker L groups, wherein the linker L comprises, for example, an ester, urea, thiourea, or thio ether group, and wherein the diameter of the nanoparticle is about 15 nm to about 200 nm. The invention also provides novel methods of making and using the silica nanoparticles described herein.
该发明提供了一种二氧化硅纳米颗粒,包括一个无孔的硅氧键基质,其中该基质包含与基质中的硅或氧原子共轭的有机试剂,这些有机试剂通过连接剂L基团与基质共轭,其中连接剂L包括例如酯、脲、硫脲或硫醚基团,纳米颗粒的直径约为15纳米到200纳米。该发明还提供了制备和使用上述二氧化硅纳米颗粒的新方法。