Butyl-dodecyl-dimethylazanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Butyl-dodecyl-dimethylazanium
• 化学式: C18H40N+
• 分子量: 270.5
• InChiKey: VQRZNCVKGHWIHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• [EN] POLYCATIONIC AMPHIPHILES AND POLYMERS THEREOF AS ANTIMICROBIAL AGENTS AND METHODS USING SAME<br/>[FR] COMPOSÉS AMPHIPHILES POLYCATIONIQUES ET LEURS POLYMÈRES UTILISABLES EN TANT QU'AGENTS ANTIMICROBIENS ET LEURS PROCÉDÉS D'UTILISATION
  申请人：TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

  公开号：WO2016172436A1

  公开（公告）日：2016-10-27

  The present invention includes novel polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes novel polymers of polycationic amphiphilic compounds useful as antimicrobial agents. The present invention further includes methods useful for removing microorganisms and/or biofilm-embedded microorganisms from a surface. The present invention further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms and/or biofilm-embedded microorganisms on a surface.

  本发明包括新型的具有抗菌作用的多阳离子两性化合物。本发明还包括新型的多阳离子两性化合物聚合物，用作抗菌剂。本发明还包括用于从表面去除微生物和/或生物膜中嵌入的微生物的方法。本发明还包括用于预防或减少微生物和/或生物膜中嵌入的微生物在表面上生长或繁殖的组合物和方法。
• [EN] BISCATIONIC AND TRISCATIONIC AMPHILES AS ANTIMICROBIAL AGENTS<br/>[FR] COMPOSÉS AMPHIPHILES BISCATIONIQUES ET TRISCATIONIQUES UTILISÉS COMME AGENTS ANTIMICROBIENS
  申请人：UNIV TEMPLE

  公开号：WO2015069760A1

  公开（公告）日：2015-05-14

  The present disclosure provides an antimicrobial composition including a compound which is a biscationic or triscationic amphiphile, and the method of making such an antimicrobial composition, and the method of using such a compound or composition for antimicrobial use. The antimicrobial composition can include a compound having the formula (I) wherein R is a methylene group unsubstituted or optionally substituted, s is an integer in the range from 1 to 6, R1, R2, R3 or R4 is H or a C 1-4 alkyl unsubstituted or optionally substituted, X is a halogen, m and n are integers in the range from 5 to 25, and m is not equal to n. Alternatively, the antimicrobial composition can comprise a compound having the formula (III) or (IV) wherein R1, R2, R3, R4 R5, or R6 is H or a C1-4 alkyl unsubstituted or optionally substituted, X or Y is a halogen, and m and n are integers in the range from 5 to 25.

  本公开提供了一种抗微生物组合物，包括一种双阳离子或三阳离子两性分子，以及制备此类抗微生物组合物的方法，以及使用此类化合物或组合物进行抗微生物用途的方法。抗微生物组合物可以包括具有以下结构式(I)的化合物，其中R是未取代或可选择取代的亚甲基基团，s是在1到6范围内的整数，R1、R2、R3或R4是H或未取代或可选择取代的C1-4烷基，X是卤素，m和n是在5到25范围内的整数，且m不等于n。或者，抗微生物组合物可以包括具有以下结构式(III)或(IV)的化合物，其中R1、R2、R3、R4、R5或R6是H或未取代或可选择取代的C1-4烷基，X或Y是卤素，m和n是在5到25范围内的整数。
• [EN] COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY- WATER SOLUBLE DRUGS<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE PRÉPARATION DE SELS IONIQUES À BAS POINT DE FUSION DE MÉDICAMENTS FAIBLEMENT HYDROSOLUBLES
  申请人：UNIV MONASH

  公开号：WO2015013772A1

  公开（公告）日：2015-02-05

  The disclosure relates generally to ionic salts, particularly low-melting ionic salts such as ionic liquids, of poorly- water soluble drugs. The disclosure further relates to methods of preparing the ionic salts of poorly-water soluble drugs, lipid formulations comprising them and their use in drug delivery.

  该披露通常涉及离子盐，特别是低熔点离子盐，例如贫水溶性药物的离子液体。该披露进一步涉及制备贫水溶性药物的离子盐的方法，包含它们的脂质配方以及它们在药物递送中的使用。
• COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY-WATER SOLUBLE DRUGS
  申请人：MW ENCAP LIMITED

  公开号：US20160151503A1

  公开（公告）日：2016-06-02

  The disclosure relates generally to ionic salts, particularly low-melting ionic salts such as ionic liquids, of poorly-water soluble drugs. The disclosure further relates to methods of preparing the ionic salts of poorly-water soluble drugs, lipid formulations comprising them and their use in drug delivery.

  本发明涉及离子盐，特别是低熔点的离子盐，例如离子液体，用于难溶于水的药物。本发明还涉及制备难溶于水的药物的离子盐的方法，包含它们的脂质配方以及它们在药物输送中的使用。
• Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds
  申请人：Panchalingam Vaithilingam

  公开号：US20050081714A1

  公开（公告）日：2005-04-21

  A method and a quaternary ammonium or phosphonium composition used therein for inhibiting retarding, mitigating, reducing, controlling and/or delaying formation of hydrocarbon hydrates or agglomerates of hydrates. The method may be applied to prevent or reduce or mitigate plugging of conduits, pipes, transfer lines, valves, and other places or equipment where hydrocarbon hydrate solids may form under the conditions. At least one quaternary ammonium or phosphonium compound is added into the process stream, where the compound may be mixed with another compound selected from other amino alcohols, esters, quaternary ammonium, phosphonium or sulphonium salts, betaines, amine oxides, amides, simple amine salts, and combinations thereof.

  一种抑制、延缓、减轻、减少、控制和/或延迟碳氢化合物水合物或水合物团聚体形成的方法及其中使用的季铵或鏻组合物。该方法可用于防止或减少或减轻导管、管道、传输线、阀门和其他在条件下可能形成烃水合物固体的地方或设备的堵塞。将至少一种季铵或鏻化合物加入工艺流中，该化合物可与选自其他氨基醇、酯、季铵盐、鏻盐或锍盐、甜菜碱、胺氧化物、酰胺、单胺盐及其组合的另一种化合物混合。