3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate
• 英文别名: (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) dihydrogen phosphate
• 化学式: C₁₈H₂₅O₅P
• 分子量: 352.4
• InChiKey: BBWXLCKRYRQQPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• EP1615650A4
  申请人：——

  公开号：EP1615650A4

  公开（公告）日：2006-06-14
• EP1615650A1
  申请人：——

  公开号：EP1615650A1

  公开（公告）日：2006-01-18
• [EN] PHOSPHATE DERIVATIVES OF PHARMACEUTICAL PRODUCTS<br/>[FR] DERIVES PHOSPHATES DE PRODUITS PHARMACEUTIQUES
  申请人：VITAL HEALTH SCIENCES PTY LTD

  公开号：WO2004091636A1

  公开（公告）日：2004-10-28

  According to the invention, there is provided a complex of a pharmaceutical compound selected from the group consisting of opioids, hormones, anaethetics and chemotherapeutic agents comprising the reaction product of: (a) one or more phosphate derivatives of one or more opioids, steroid hormones, thyroid hormones, anaesthetics or chemotherapeutic agents having a phenolic, primary alcohol, secondary alcohol or tertiary hydroxyl group; and (b) a complexing agent selected from the group comprising amphoteric surfactants, cationic surfactants, amino acids having nitrogen functional groups and proteins rich in these amino acids.