Cyclopropyl-trimethylammonium | 89065-32-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Cyclopropyl-trimethylammonium
• 英文别名: Cyclopropyl(trimethyl)azanium
• CAS: 89065-32-7
• 化学式: C₆H₁₄N
• 分子量: 100.184
• InChiKey: WYFGXQCOMIYMIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA)
  申请人：The Procter & Gamble Company

  公开号：US20190099389A1

  公开（公告）日：2019-04-04

  A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual by providing a composition comprising a compound set forth in Formula (I):

  通过提供包含式(I)中所列化合物的组合物，抑制胆碱转化为三甲胺（TMA）并降低个体体内的TMAO的方法。
• [EN] PROCESS FOR THE PREPARATION OF ROFLUMILAST<br/>[FR] PROCEDE DE PREPARATION DE ROFLUMILAST
  申请人：RANBAXY LAB LTD

  公开号：WO2005026095A1

  公开（公告）日：2005-03-24

  The present invention relates to a process for the preparation of 3-cyclopropylmethoxy-4-difluromethoxy benzoic acid of structural Formula I, and to the use of this compound as an intermediate for the preparation of roflumilast.

  本发明涉及一种制备结构式I中的3-环丙基甲氧基-4-二氟甲氧基苯甲酸的方法，以及将该化合物用作制备洛氟米拉斯特的中间体的用途。
• BOROPEPTIDE INHIBITORS OF ENTEROPEPTIDASE AND THEIR USES IN TREATMENT OF OBESITY, OVERWEIGHT AND/OR DISEASES ASSOCIATED WITH AN ABNORMAL FAT METABOLISM
  申请人：Harosh Itzik

  公开号：US20100311690A1

  公开（公告）日：2010-12-09

  The present invention relates to novel compounds, particularly derivatives of boroarginine, boroornithine and borolysine that selectively modulate, regulate, and/or inhibit enteropeptidase. The invention also relates to compositions, particularly pharmaceutical compositions, as well as methods to treat excess weight, obesity and diseases associated with an abnormal fat metabolism.

  本发明涉及新型化合物，特别是硼精氨酸衍生物、硼鸟氨酸衍生物和硼赖氨酸衍生物，它们能够选择性地调节、调控和/或抑制肠肽酶。本发明还涉及组合物，特别是制药组合物，以及治疗过度体重、肥胖和与异常脂肪代谢相关的疾病的方法。
• Methods for inhibiting conversion of choline to trimethylamine (TMA)
  申请人：The Procter & Gamble Company

  公开号：US10675256B2

  公开（公告）日：2020-06-09

  A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual by providing a composition comprising a compound set forth in Formula (I):

  一种通过提供包含式 (I) 所述化合物的组合物来抑制胆碱向三甲胺 (TMA) 的转化并降低个体体内 TMAO 的方法：
• PROCESS FOR THE PREPARATION OF ROFLUMILAST
  申请人：Ranbaxy Laboratories Limited

  公开号：EP1670742A1

  公开（公告）日：2006-06-21