Tetra(propan-2-yl)azanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Tetra(propan-2-yl)azanium
• 化学式: C12H28N+
• 分子量: 186.36
• InChiKey: XAMMKFSEEQGBIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Ammonium Fluoroalkanesulfonates and a Synthesis Method Therefor
  申请人：Nagamori Masashi

  公开号：US20120004447A1

  公开（公告）日：2012-01-05

  An ammonium hydroxyfluoroalkanesulfinate is obtained by using an organic base while sulfinating a bromofluoroalcohol with a sulfinating agent. An ammonium hydroxyfluoroalkanesulfonate is obtained by oxidizing the ammonium hydroxyfluoroalkanesulfinate. An onium fluoroalkanesulfonate is obtained by converting the ammonium hydroxyfluoroalkanesulfonate into an onium salt through esterification. This onium fluoroalkanesulfonate is useful as a photoacid generator in chemically amplified resists and the like.

  一种氢氧基氟烷磺酸铵是通过在磺化剂的作用下使用有机碱对溴氟醇进行磺化而获得的。将氢氧基氟烷磺酸铵氧化后得到一种氢氧基氟烷磺酸铵盐。通过酯化将氢氧基氟烷磺酸铵转化为一种离子氟烷磺酸盐。这种离子氟烷磺酸盐在化学增感抗蚀剂等中作为光酸发生剂是有用的。
• Compounds for non-invasive measurement of aggregates of amyloid peptides
  申请人：Technische Universität München

  公开号：EP2218464A1

  公开（公告）日：2010-08-18

  The invention relates to the provision of compounds, methods for producing them, and their use for imaging and quantification of aggregates of amyloid peptides in vivo. In a preferred aspect of the invention, a tracer is administered to humans and displays enrichment in the areas that are containing amyloid plaques. Tracers of the invention can be used for in vivo visualization and quantification of aggregates of amyloid peptides in patients affected diseases characterized in the generation of aggregates of amyloid peptides, for example familial or sporadic Alzheimer's disease and type II diabetes. Tracers of the invention can be used for monitoring effects of amyloid-modulating therapies of patients affected with diseases characterized in the generation of aggregates of amyloid peptides, for example familial or sporadic Alzheimer's disease and type II diabetes.

  该发明涉及化合物的提供、生产方法以及它们在体内成像和定量淀粉样肽聚集物的用途。在该发明的一个优选方面，向人类施用一种示踪剂，并且在含有淀粉样斑块的区域显示富集。该发明的示踪剂可用于患有以生成淀粉样肽聚集物为特征的疾病的患者体内成像和定量，例如家族性或散发性阿尔茨海默病和2型糖尿病。该发明的示踪剂可用于监测患有以生成淀粉样肽聚集物为特征的疾病的患者对调节淀粉样蛋白的疗法的影响，例如家族性或散发性阿尔茨海默病和2型糖尿病。
• Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and their use
  申请人：E.R. SQUIBB & SONS, INC.

  公开号：EP0463456A1

  公开（公告）日：1992-01-02

  Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have the structure wherein R is OH, or salts thereof or lower alkoxy; Rx is H or alkyl; R1 is lower alkyl; R2 is lower alkyl; R3 is phenyl or substituted phenyl; and R4 is phenyl or substituted phenyl. New pharmaceutical compositions containing such compounds especially oral dosage forms, and use of such compounds for the preparation of a pharmaceutical composition to inhibit cholesterol biosynthesis are also described.

  提供了一种作为胆固醇生物合成抑制剂和降胆固醇药物有用的化合物，其结构为其中R为OH，或其盐或较低的烷氧基；Rx为H或烷基；R1为较低的烷基；R2为较低的烷基；R3为苯基或取代苯基；以及R4为苯基或取代苯基。还描述了含有这种化合物的新药物组合物，特别是口服剂型，以及利用这种化合物制备用于抑制胆固醇生物合成的药物组合物。
• FLUORINATED IMIDE SALT COMPOUND AND SURFACTANT
  申请人：Mitsubishi Materials Electronic Chemicals Co., Ltd.

  公开号：US20210355080A1

  公开（公告）日：2021-11-18

  A fluorinated imide salt compound of the present invention is a compound represented by General Formula (1). In General Formula (1), m represents 1 or 2, n represents an integer from 1 to 4, α represents 1 or 2, and X α+ represents an α-valent metal ion, a primary ammonium ion, a secondary ammonium ion, a tertiary ammonium ion, a quaternary ammonium ion, or NH 4 + .

  本发明的氟化亚胺盐化合物是由通式（1）表示的化合物。在通式（1）中，m代表1或2，n代表1到4之间的整数，α代表1或2，X α+ 代表α价金属离子，一价铵离子，二价铵离子，三价铵离子，季铵离子或NH 4 + 。
• Fluoroalkanesulfonic Acid Ammonium Salts and Method for Producing Same
  申请人：Nagamori Masashi

  公开号：US20110313190A1

  公开（公告）日：2011-12-22

  When sulfinating a carboxylic acid bromofluoroalkyl ester by using a sulfinating agent, an organic base is used, thereby obtaining a fluoroalkanesulfinic acid ammonium salt. This is oxidized to obtain a fluoroalkanesulfonic acid ammonium salt. This is used as the raw material and is converted to an onium salt or is converted to an onium salt by going through saponification and esterification, thereby obtaining a fluoroalkanesulfonic acid onium salt. This fluoroalkanesulfonic acid onium salt is useful as a photoacid generator used for chemically amplified resist materials, etc.

  在使用亚砜化剂对羧酸溴氟烷基酯进行亚砜化时，使用有机碱，从而获得氟烷磺酸铵盐。将其氧化得到氟烷磺酸铵盐。将其用作原料，通过皂化和酯化转化为离子盐，从而获得氟烷磺酸离子盐。这种氟烷磺酸离子盐可用作用于化学增感型抗蚀材料等的光酸发生剂。