Triethyl(prop-2-ynyl)azanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Triethyl(prop-2-ynyl)azanium
• 化学式: C9H18N+
• 分子量: 140.25
• InChiKey: SLBYVUVUEZZLDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Purification Strategy for Direct Nucleophilic Procedures
  申请人：Cyr John

  公开号：US20110112293A1

  公开（公告）日：2011-05-12

  The present invention provides novel and advantageous processes for preparing and purifying chemical compounds such as pharmaceuticals. The processes comprise a nucleophilic substitution reaction with a moiety X wherein the leaving group L of a substrate S in the reaction is covalently attached to a purification moiety M. This concept offers a convenient and lime-saving way to purity the desired product S-X from non-reacted precursors S-L-M and by-products L-M.

  本发明提供了一种新颖和有利的制备和纯化化学化合物，如药物的方法。该方法包括使用一个官能团X进行亲核取代反应，其中反应底物S的离去基团L共价地连接到纯化官能团M上。这个概念提供了一种方便和节省时间的方法，以从未反应的前体S-L-M和副产物L-M中纯化所需的产品S-X。
• [EN] PURIFICATION STRATEGY FOR DIRECT NUCLEOPHILIC PROCEDURES<br/>[FR] STRATÉGIE D'ÉPURATION POUR PROCESSUS NUCLÉOPHILIQUES DIRECTS
  申请人：BAYER SCHERING PHARMA AG

  公开号：WO2009127372A1

  公开（公告）日：2009-10-22

  The present invention provides novel and advantageous processes for preparing and purifying chemical compounds such as pharmaceuticals. The processes comprise a nucleophilic substitution reaction with a moiety X wherein the leaving group L of a substrate S in the reaction is covalently attached to a purification moiety M. This concept offers a convenient and time-saving way to purify the desired product S-X from non-reacted precursors S-L-M and by-products L-M.