2-[(3-Hexadecylsulfanylcyclohexyl)oxy-hydroxyphosphoryl]oxyethyl-trimethylazanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-[(3-Hexadecylsulfanylcyclohexyl)oxy-hydroxyphosphoryl]oxyethyl-trimethylazanium
• 化学式: C27H57NO4PS+
• 分子量: 522.8
• InChiKey: RRJNHRZHTMBPEI-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  34
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  81.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Lipid analogs for treating viral infections
  申请人：Kucera S. Louis

  公开号：US20050080050A1

  公开（公告）日：2005-04-14

  A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.

  本发明揭示了一种治疗病毒感染，特别是HIV-1、乙型肝炎病毒和疱疹病毒的方法。该方法包括向需要这种治疗的受试者注射一定量的磷脂或磷脂衍生物以控制感染。
• Lipid analogs for inhibiting HIV-1 activity
  申请人：Kucera S. Louis

  公开号：US20070105812A1

  公开（公告）日：2007-05-10

  The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.

  该发明涉及治疗病毒感染的方法，特别是乙型肝炎病毒。该方法包括向需要此类治疗的受试者施用控制感染量的磷脂或磷脂衍生物，以抑制病毒感染的活动。
• Lipid analogs for combating tumors
  申请人：Kucera S. Louis

  公开号：US20070099870A1

  公开（公告）日：2007-05-03

  The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.

  本发明涉及治疗病毒感染的方法，特别是乙型肝炎病毒。该方法包括向需要此类治疗的受试者施用控制感染的磷脂或磷脂衍生物的治疗量，以抑制病毒感染的活动。
• Lipid analogs for inhibiting the activity of hepatitis B antigen
  申请人：Kucera S. Louis

  公开号：US20070105811A1

  公开（公告）日：2007-05-10

  The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.

  本发明涉及治疗病毒感染的方法，特别是乙型肝炎病毒。该方法包括向需要此类治疗的受试者施用足以控制感染的磷脂或磷脂衍生物的量，以抑制病毒感染的活性。
• LIPID ANALOGS FOR TREATING VIRAL INFECTIONS
  申请人：WAKE FOREST UNIVERSITY

  公开号：EP0781138B1

  公开（公告）日：2008-05-21