1-Tert-butyl-7-(2,5-diazabicyclo[2.2.1]heptan-2-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid | 116143-32-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 1-Tert-butyl-7-(2,5-diazabicyclo[2.2.1]heptan-2-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• CAS: 116143-32-9
• 化学式: C₁₈H₂₁FN₄O₃
• 分子量: 360.4
• InChiKey: KNHLHFDFFDCJJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  85.8
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• COMPOSITION COMPRISING AN ANTIBIOTIC AND A CORTICOSTEROID
  申请人：Freehauf Keith A.

  公开号：US20100087409A1

  公开（公告）日：2010-04-08

  This invention relates to compositions (e.g., otic compositions) comprising an antibiotic (generally a quinolone or naphthyridinone), corticosteroid, and organic acid (generally a fatty acid). This invention also relates to treatment methods using such a composition, uses of such a composition to make medicaments, and therapeutic kits comprising such a composition.
• [EN] COMPOSITION COMPRISING AN ANTIBIOTIC AND A CORTICOSTEROID<br/>[FR] COMPOSITION COMPRENANT UN ANTIBIOTIQUE ET UN CORTICOSTÉROÏDE
  申请人：INTERVET INT BV

  公开号：WO2009147144A2

  公开（公告）日：2009-12-10

  This invention relates to compositions (e.g., otic compositions) comprising an antibiotic (generally a quinolone or naphthyridinone), corticosteroid, and organic acid (generally a fatty acid). This invention also relates to treatment methods using such a composition, uses of such a composition to make medicaments, and therapeutic kits comprising such a composition.