聚丙二醇,异佛尔酮二异氰酸酯聚合物 | 39323-37-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 聚丙二醇,异佛尔酮二异氰酸酯聚合物
• 英文名称: 5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane;propane-1,3-diol
• CAS: 39323-37-0；227099-98-1
• 化学式: C15H26N2O4
• 分子量: 298.38
• InChiKey: FXQJGIVHZAPZJM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  99.3
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• MEDICAL TOOLS AND DEVICES WITH IMPROVED ULTRASOUND VISIBILITY
  申请人：Nycomed Amersham PLC

  公开号：EP1155418A1

  公开（公告）日：2001-11-21
• US6749554B1
  申请人：——

  公开号：US6749554B1

  公开（公告）日：2004-06-15
• [EN] MEDICAL TOOLS AND DEVICES WITH IMPROVED ULTRASOUND VISIBILITY<br/>[FR] INSTRUMENT OU OUTIL MEDICAL A VISIBILITE AMELIOREE AUX ULTRASONS
  申请人：NYCOMED AMERSHAM PLC

  公开号：WO2000051136A1

  公开（公告）日：2000-08-31

  A medical or surgical device or tool that is designed to be implanted or inserted inside the human or mammalian body, having at least part of its surface coated whereby the ultrasound visibility of said device or tool in vivo is enhanced, wherein the coating comprises one or more of the following: (i) a matrix material containing a plurality of contrast enhancing elements; (ii) magnesium; (iii) a liquid or polymer which alters its ultrasound imaging properties upon elevating the temperature from ambient to physiological temperature; (iv) a liquid or polymer which alters its ultrasound imaging properties as a result of a change in pH; (v) an essentially non-polymeric bio-compatible compound which forms a discontinuous coating. Preferably the device or tool is a radioactive source for use in brachytherapy, and in particular a radioactive seed.