Compounds of formula I:
and pharmaceutically acceptable salts, solvates, or hydrates thereof, pharmaceutical compositions comprising the compounds of formula I, and methods of making and using the compounds, salts, solvates, or hydrates and the compositions in the treatment of various disorders associated with CRM1 activity.
式 I 的化合物:
及其药学上可接受的盐、溶液或
水合物,包含式 I 化合物的药物组合物,以及制造和使用该化合物、盐、溶液或
水合物及组合物治疗与 CRM1 活性相关的各种疾病的方法。