2-Ethyl-3-methyltetrahydrothiophene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫杂环戊烷
• 英文名称: 2-Ethyl-3-methyltetrahydrothiophene
• 英文别名: 2-ethyl-3-methylthiolane
• 化学式: C₇H₁₄S
• 分子量: 130.25
• InChiKey: XNZCGHZDGZDSBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• BORONIC ACID INHIBITORS OF HIV PROTEASE
  申请人：WISCONSIN ALUMINI RESEARCH FOUNDATION

  公开号：US20160122366A1

  公开（公告）日：2016-05-05

  Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p-B(OH) 2 -phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected. Methods for treating AIDS and ARC as well as providing a method for treating or preventing HIV infection
• Boronic Acid Inhibitors of HIV Protease
  申请人：Wisconsin Alumni Research Foundation

  公开号：US20170327517A1

  公开（公告）日：2017-11-16

  Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p-B(OH) 2 -phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected. Methods for treating AIDS and ARC as well as providing a method for treating or preventing HIV infection
• US4710320A
  申请人：——

  公开号：US4710320A

  公开（公告）日：1987-12-01
• US8722917B2
  申请人：——

  公开号：US8722917B2

  公开（公告）日：2014-05-13
• US9738664B2
  申请人：——

  公开号：US9738664B2

  公开（公告）日：2017-08-22