Dimethyldioctadecylammonium bromide, >=98% (TLC)

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Dimethyldioctadecylammonium bromide, >=98% (TLC)
• 英文别名: dimethyl(dioctadecyl)azanium;hydrobromide
• 化学式: C38H81BrN+
• mdl: MFCD00041975
• 分子量: 632.0
• InChiKey: PSLWZOIUBRXAQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.12
• 重原子数：
  40
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  1
• 氢受体数：
  0

文献信息

• EMULSION ADJUVANT FOR INTRAMUSCULAR, INTRADERMAL AND SUBCUTANEOUS ADMINISTRATION
  申请人：The Regents of The University of Michigan

  公开号：EP3454891A1

  公开（公告）日：2019-03-20
• [EN] EMULSION ADJUVANT FOR INTRAMUSCULAR, INTRADERMAL AND SUBCUTANEOUS ADMINISTRATION<br/>[FR] ADJUVANT EN ÉMULSION POUR ADMINISTRATION INTRAMUSCULAIRE, INTRADERMIQUE ET SOUS-CUTANÉE
  申请人：UNIV MICHIGAN REGENTS

  公开号：WO2017196979A1

  公开（公告）日：2017-11-16

  The present invention provides compositions comprising emulsion adjuvant and one or more active agents or substances formulated for infusion or injection into a subject (e.g.,using a syringe and needle), as well as methods of formulating and using the same (e.g., as an injectable medicinal composition (e.g., a vaccine)). The emulsion adjuvant of an immunogenic composition of the invention in its preferred form comprises a cationic lipid containing a polar head group and a hydrophobic component (e.g., a dual chain hydrophobic group (e.g., the cationic surfactant dioctadecyl dimethyl ammonium chloride (DODAC) and dioctadecyl dimethyl ammonium bromine (DODAB))). Compositions of the invention comprising emulsion adjuvant and one or more active agents or substances formulated for administration via injection to a subject find use in treatment and/or prevention of infectious disease, cancer and/or allergy.