7-Methoxy-1,1-dimethyl-1,2-dihydro-xanthen-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 7-Methoxy-1,1-dimethyl-1,2-dihydro-xanthen-3-one
• 英文别名: 7-methoxy-1,1-dimethyl-2H-xanthen-3-one
• 化学式: C₁₆H₁₆O₃
• 分子量: 256.301
• InChiKey: ONFDVNFEXMXGRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-Ethoxy-7-methoxy-1,1-dimethyl-1,2-dihydro-xanthenylium; perchlorate 在 sodium acetate 作用下， 以 水 、 丙酮 为溶剂， 以95%的产率得到7-Methoxy-1,1-dimethyl-1,2-dihydro-xanthen-3-one
  参考文献：
  名称：

  摘要：

  1,3-Diethoxy-2-R-5,5-R-1,R-1-1-cyclohexenylium perchlorates in condensation with 2-hydroxyaryl-aldehydes under dehydration conditions give rise to 3-ethoxy-1,2-dihydroxanthylium perchlorates that with the second molecule of 2-hydroxyarylaldehyde afford 13H-chromeno[3,2-b]xanth-5-ylium perchlorates, and with primary and secondary amines yield 3-(R-2,R-3-amino)-1,2-dihydroxanthylium perchlorates. The condensation of 2-bromodimedone with salicylaldehydes in triethyl orthoformate and perchloric acid medium furnished 6-bromo-13,13-dimethyl-13H-chromeno[3,2-b]xanth-5-ylium perchlorates. The latter compounds show strong fluorescence in 530-630 nm region with 0.48-0.98 quantum efficiency. Under similar conditions the dimedone and 2-acetyldimedone afford with 2-hydroxyarylaldehydes tris-condensation products: 2,10-dimethoxy-6-(3-methoxy-6-oxo-2,4-cyclohexadienylidenemethyl)-7,7-dimethyl-7H-chromeno[2,3-a]-xanth-13-ylium perchlorate and 2,10-dimethoxy-6-(6-methoxychromylium-2-yl)-13,13-dimethyl-13H-chromeno[3,2-b]xanth-5-ylium diperchlorate respectively.

  DOI：

  10.1023/a:1012433903229

文献信息

• US8569360B2
  申请人：——

  公开号：US8569360B2

  公开（公告）日：2013-10-29