2-Pyridin-3-yl-5-[(2-pyridin-3-yl-1,3-benzoxazol-5-yl)sulfonyl]-1,3-benzoxazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑类
• 英文名称: 2-Pyridin-3-yl-5-[(2-pyridin-3-yl-1,3-benzoxazol-5-yl)sulfonyl]-1,3-benzoxazole
• 化学式: C₂₄H₁₄N₄O₄S
• 分子量: 454.5
• InChiKey: SQTJTALRWRAGIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  120
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• WNT PROTEIN SIGNALLING INHIBITORS
  申请人：The Board of Regents of the University of Texas System

  公开号：US20150157633A1

  公开（公告）日：2015-06-11

  The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.