3,3-Dichloro-2,2,4,4-tetramethylpentan | 79991-69-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 3,3-Dichloro-2,2,4,4-tetramethylpentan
• 英文别名: 3,3-dichloro-2,2,4,4-tetramethylpentane；Markewicz's reagent；tBu2SiCl2；Pentane, 3,3-dichloro-2,2,4,4-tetramethyl-
• CAS: 79991-69-8
• 化学式: C₉H₁₈Cl₂
• 分子量: 197.148
• InChiKey: ZUAWOFHXVSGUAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  3,3-Dichloro-2,2,4,4-tetramethylpentan 生成 tetra-tert-butylethylene
  参考文献：
  名称：

  KREBS, A.;BORN, W.;KALETTA, B.;NICKEL, W. -U.;RUEGER, W., TETRAHEDRON LETT., 1983, 24, N 44, 4821-4824

  摘要：

  DOI：
• 作为产物：
  描述：

  3-diazo-2,2,4,4-tetramethylpentane 生成 3,3-Dichloro-2,2,4,4-tetramethylpentan
  参考文献：
  名称：

  Sterisch gehinderte alkene - VI. Auf dem weg zum tetra-tert.butylethen

  摘要：

  DOI：

  10.1016/s0040-4039(00)94016-4

文献信息

• 2′-O-Appended Polyamines that Increase Triple-Helix-Forming Oligonucleotide Affinity are Selected by Dynamic Combinatorial Chemistry
  作者：Laurent Azéma、Katell Bathany、Bernard Rayner

  DOI：10.1002/cbic.201000538

  日期：2010.12.10

  Stability leads to selection: Cationic appending groups on a triplex‐forming oligonucleotide (TFO) designed to bind a DNA target can be rapidly selected from a small library of various amines and polyamines for their capacity to stabilize triple‐helix formation.

  稳定性导致选择：设计用于结合DNA靶标的三链形成寡核苷酸（TFO）上的阳离子附加基团可从各种胺和多胺的小型文库中快速选择，以稳定三螺旋的形成。
• METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM
  申请人：JSR Corporation

  公开号：EP1705206A1

  公开（公告）日：2006-09-27

  There are provided a method for producing a polymer, a polymer, an insulating-film-forming composition, a method for producing an insulating film, and an insulating film capable of forming a film which is suitably used as an interlayer dielectric for semiconductor devices or the like and exhibits a low relative dielectric constant, excellent mechanical strength and adhesion, and uniform quality. A method for producing a polymer of the invention comprises hydrolyzing and condensing (B) a hydrolyzable-group-containing silane monomer in the presence of (A) a polycarbosilane, the polycarbosilane (A) being a polymer (I) obtained by reacting (a) a compound shown by the following general formula (1) and (b) at least one compound selected from the group consisting of a compound shown by the following general formula (2) and a compound shown by the following general formula (3) in an organic solvent in the presence of at least one of an alkali metal and an alkaline earth metal,         R1kCX4-k     (1)         R2kSiY4-k     (2)         R3mY3-mSiCR4nX3-n     (3) wherein R1 to R4 individually represent a monovalent organic group or a hydrogen atom, X represents a halogen atom, Y represents a halogen atom or an alkoxy group, k represents an integer from 0 to 3, and m and n individually represent integers from 0 to 2.

  本发明提供了一种聚合物的生产方法、一种聚合物、一种绝缘成膜组合物、一种绝缘膜的生产方法，以及一种能够形成薄膜的绝缘膜，该薄膜适合用作半导体器件或类似器件的层间电介质，并具有较低的相对介电常数、优异的机械强度和附着力以及均匀的质量。 生产本发明聚合物的方法包括在（A）聚碳酸酯硅烷存在下水解和缩合（B）含可水解基团的硅烷单体、聚碳硅烷(A)为聚合物(I)，由(a)下式(1)所示化合物和(b)至少一种选自下式(2)所示化合物和下式(3)所示化合物组成的组的化合物在有机溶剂中，在碱金属和碱土金属中至少一种存在下反应而得、 R1kCX4-k (1) R2kSiY4-k (2) R3mY3-mSiCR4nX3-n (3) 其中 R1 至 R4 分别代表一价有机基团或氢原子，X 代表卤素原子，Y 代表卤素原子或烷氧基，k 代表 0 至 3 的整数，m 和 n 分别代表 0 至 2 的整数。
• Hydrolysis resistant sialic acid derivatives and methods for their use
  申请人：The University of British Columbia

  公开号：US10023601B2

  公开（公告）日：2018-07-17

  This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, improved biological stability or an improved pharmacokinetic property.

  本发明提供具有式结构的化合物：此外，还提供了此类化合物与糖受体共价键合的方法和用途，以形成具有减少酶水解、提高生物稳定性或改善药代动力学特性的改性蛋白质治疗剂。
• Quinazoline and indole compounds to treat medical disorders
  申请人：Achillion Pharmaceuticals, Inc.

  公开号：US10961252B2

  公开（公告）日：2021-03-30

  Compounds, methods of use, and processes for making inhibitors of Complement Factor B are provided.

  本研究提供了用于制造补体因子 B 抑制剂的化合物、使用方法和工艺。
• DNMR investigations on 3,3-Dihalo-2,2,4,4-tetramethylpentanes
  作者：Hans-Otto Kalinowski、Erwin Röcker、Günther Maier

  DOI：10.1002/omr.1270210117

  日期：1983.1

  AbstractThe 1H and 13C NMR spectra of 3,3,‐diiodotetramethylpentane (2), 3,3‐dibromotetramethylpentane (3), and 3,3‐dichlorotetramethylpentane (4) are temperature dependent. The activation parameters for the tert‐butyl group rotation in 2–4 have been determined. The 13C NMR chemical shifts are discussed.

表征谱图