tetrakis-N-(2-hydroxy-ethyl)-p-phenylenediamine | 25538-96-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: tetrakis-N-(2-hydroxy-ethyl)-p-phenylenediamine
• 英文别名: Tetrakis-N-(2-hydroxy-aethyl)-p-phenylendiamin；2-[4-[bis(2-hydroxyethyl)amino]-N-(2-hydroxyethyl)anilino]ethanol
• CAS: 25538-96-9
• 化学式: C₁₄H₂₄N₂O₄
• 分子量: 284.356
• InChiKey: QOXGGCVXTAOYLP-UHFFFAOYSA-N

物化性质

• 沸点：
  548.5±50.0 °C(Predicted)
• 密度：
  1.283±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  87.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  tetrakis-N-(2-hydroxy-ethyl)-p-phenylenediamine 在 氯仿 、 五氯化磷 作用下， 生成 tetrakis-N-(2-chloro-ethyl)-p-phenylenediamine
  参考文献：
  名称：

  43.芳基-2-卤代烷基胺。第一部分

  摘要：

  DOI：

  10.1039/jr9490000183
• 作为产物：
  描述：

  对苯二胺 、 2-氯乙醇 在 sodium hydroxide 作用下， 生成 tetrakis-N-(2-hydroxy-ethyl)-p-phenylenediamine
  参考文献：
  名称：

  A hemilabile binucleating pincer ligand for self-assembly of coordination oligomers and polymers

  摘要：

  双（PNP）供体钳形配体 1,4-C6H4{N(CH2CH2PPh2)2}2，1，含有弱碱性氮供体原子，因为孤对电子与桥接的亚苯基共轭，这一特点可用于合成低聚物和聚合物。X=Cl、Br 或 OTf 的[Pd2X2(µ-1)](OTf)2 复合物含有双（钳形）结合模式（µ-κ6-P4N2）的配体 1，但[Pd4Cl6(µ3-1)2]Cl2 则含有不对称的µ3-κ5-P4N 结合模式的配体。溴化物配合物被认为是一种聚合物[{Pd2Br4(µ4-1)}n]，配体 1 以 µ4-κ4-P4 结合模式存在。甲基铂（II）配合物[Pt2Me4(µ-1)]和[Pt2Me2(µ-1)](O2CCF3)2含有以µ-κ4-P4和µ-κ6-P4N2结合模式存在的配体1，而银（I）配合物[Ag2(O2CCF3)2 (µ-1)]含有以中间结合模式存在的配体1，其中氮供体的配位非常弱。复合物 [Pd2(OTf)2(µ-1)](OTf)2 和 [Ag2(O2CCF3)2(µ-1)] 与 4,4′-联吡啶反应生成聚合物 [Pd2(µ-bipy)(µ-1)](OTf)4 和 [Ag2(µ-bipy)(µ-1)](O2CCF3)2。

  DOI：

  10.1039/b716035f

文献信息

• Method and device for specific binding assay
  申请人：MOCHIDA PHARMACEUTICAL CO., LTD.

  公开号：EP0690306A1

  公开（公告）日：1996-01-03

  This invention provides a specific binding assay method which is excellent in general purpose applicability and can perform highly accurate and quick measurement effected by the exclusion of various factors that decrease reliability of the measured values, such as non-specific reactants in test samples, assay conditions and inactivation and the like changes in the activity of reagents, as well as a specific binding assay device suitable for the practice thereof. This object is achieved by allowing a signal substance generator which takes part in a specific binding reaction and generates a signal substance, together with a liquid sample, to flow through a predetermined channel in a predetermined direction, thereby effecting generation of the specific binding reaction of a substance to be assayed to form a distribution of the signal substance generator in the channel in response to the concentration of the substance to be assayed, allowing the signal substance generator distributed in the channel to generate the signal substance, detecting the generated signal substance by a plurality of detection means arranged at different positions in the liquid flow direction, and arithmetically processing the plural detection results to minimize influence of other factors than the concentration of the substance to be assayed upon the assay result.

  本发明提供了一种特异性结合测定方法，它具有良好的通用性，并能排除各种降低测定值可靠性的因素，如测试样品中的非特异性反应物、测定条件和试剂活性的失活和类似变化，从而进行高度准确和快速的测定，本发明还提供了一种适用于本发明的特异性结合测定装置。 为实现这一目标，可让参与特异性结合反应并产生信号物质的信号物质发生器与液体样品一起沿预定方向流经预定通道，从而产生待测物质的特异性结合反应，使信号物质发生器在通道中形成与待测物质浓度相应的分布、让分布在通道中的信号物质发生器产生信号物质，通过布置在液体流动方向不同位置的多个检测装置检测所产生的信号物质，并对多个检测结果进行算术处理，以尽量减少除待测物质浓度以外的其他因素对检测结果的影响。
• Assay utilizing hydrogen peroxide adduct
  申请人：MOCHIDA PHARMACEUTICAL CO., LTD.

  公开号：EP0781850A2

  公开（公告）日：1997-07-02

  Improvement in assays utilizing at least hydrogen peroxide for one analysis reagent is provided. The assay of the present invention employs a stable hydrogen peroxide adduct in dry state which has no adverse effects on the assay, and which has a high hydrogen peroxide-retaining ability. In the assay, an aqueous solution is added to an adduct in dry state of (a) at least one member selected from the group consisting of a carboxylic acid and a salt thereof, phosphoric acid and a salt thereof, and a sulfonic acid and a salt thereof, and (b) hydrogen peroxide to generate peroxide, and the thus generated peroxide is used for the analysis reagent.

  本发明改进了至少使用过氧化氢作为一种分析试剂的检测方法。本发明的化验方法采用了一种稳定的干燥状态过氧化氢加合物，它对化验没有不良影响，而且具有很强的过氧化氢保留能力。在检测中，将水溶液添加到(a)至少一种选自羧酸及其盐、磷酸及其盐、磺酸及其盐和(b)过氧化氢的干态加合物中以生成过氧化氢，由此生成的过氧化氢用于分析试剂。
• ANALYZER FOR LIQUID SAMPLES
  申请人：MOCHIDA PHARMACEUTICAL CO., LTD.

  公开号：EP1043588A1

  公开（公告）日：2000-10-11

  An analyzer for liquid samples, comprising a liquid sample introduction member, a filter member for capturing a solid component of a liquid sample introduced from the liquid sample introduction member, and an analyzer member for analyzing an object substance in the liquid sample passed through the filter, wherein a clearance-carrying flow passage securing member is formed so that the permeation of a liquid component in the liquid sample is not prevented by the solid component captured by and accumulated on the filter member between a member, which is provided above the filter member, and the filter member; a specific binding analysis method and a specific binding analysis apparatus.

  一种用于液体样品的分析仪，包括液体样品导入部件、用于捕获从液体样品导入部件导入的液体样品中的固体成分的过滤部件，以及用于分析通过该过滤器的液体样品中的目标物质的分析部件，其中形成了一个间隙承载流道固定部件，以便液体样品中的液体成分的渗透不会被过滤部件捕获并积聚在过滤部件和过滤部件之间的固体成分所阻碍，该部件设置在过滤部件上方；一种特定结合分析方法和一种特定结合分析装置。
• Electrochemical assay method and novel p-phenylenediamine compound
  申请人：MOCHIDA PHARMACEUTICAL CO., LTD.

  公开号：EP0663446B1

  公开（公告）日：2000-03-22
• ELEKTROCHEMISCHER EINWEGBIOSENSOR FÜR DIE QUANTITATIVE BESTIMMUNG VON ANALYTKONZENTRATIONEN IN FLÜSSIGKEITEN
  申请人：Albatros Technologies GmbH & Co. KG

  公开号：EP1307583B1

  公开（公告）日：2005-07-20