Phenoxazine-10-acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: Phenoxazine-10-acetic acid
• 英文别名: 2-phenoxazin-10-ylacetic acid
• 化学式: C₁₄H₁₁NO₃
• 分子量: 241.24
• InChiKey: YNBDTIKGNUBBEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME
  申请人：Kokeguchi Noriyuki

  公开号：US20100091353A1

  公开（公告）日：2010-04-15

  Provided is a novel electrochemical display element which performs bright white display, high contrast black/white display and full-color display with a simple member configuration. A method for driving such display element is also provided. The display element contains an electrochromic compound, which is colored or has its color disappear due to oxidation or reduction, a metallic salt compound, an electrolyte and a white scattered material, between opposing electrodes. The display element substantially performs multiple color display of three colors or more, i.e., black display, white display and colored display other than black, by driving operation of the opposing electrodes.
• US8014056B2
  申请人：——

  公开号：US8014056B2

  公开（公告）日：2011-09-06
• [EN] USE OF 9-OXOACRIDINE-10-ACETIC ACID AND/OR SALTS AND/OR ITS ESTERS THEREOF FOR THE TREATMENT AND PROPHYLAXIS OF MALIGNANT TUMORS OF FEMALE REPRODUCTIVE SYSTEM<br/>[FR] UTILISATION D'ACIDE 9-OXOACRIDINE-10-ACÉTIQUE ET/OU DE SELS ET/OU D'ESTERS DE CELUI-CI POUR LE TRAITEMENT ET LA PROPHYLAXIE DE TUMEURS MALIGNES DE L'APPAREIL GÉNITAL FÉMININ
  申请人：SURKOV KIRILL GENNEDIEVICH

  公开号：WO2008121029A2

  公开（公告）日：2008-10-09

  [EN] The present invention relates to the treatment and/or prophylaxis of tumor reccurence in organs of a female reproductive system. According to the invention, a method of combination therapy is provided, the method including the steps of: (a) administering an effective amount of 9-oxoacridine-10-acetic acid and/or pharmaceutically acceptable salts and/or esters thereof to a patient in need thereof, and (b) hormonotherapy aimed at lowering the aromatase enzyme activity. The proposed method is useful in treatment of breast cancer, cancer uteri, ovarian cancer.
  [FR] La présente invention concerne le traitement et/ou la prophylaxie de la récurrence de tumeurs dans les organes de l'appareil génital féminin. L'invention propose une méthode de polythérapie qui comprend les étapes consistant : (a) à administrer une dose efficace d'acide 9-oxoacridine-10-acétique et/ou de sels et/ou d'esters de celui-ci acceptables sur le plan pharmaceutique à un patient nécessitant un tel traitement; et (b) à faire suivre au patient une hormonothérapie destinée faire baisser l'activité de l'enzyme aromatase. La méthode proposée est utile dans le traitement du cancer du sein, du cancer de l'utérus, et du cancer des ovaires.