N-[(E)-2-(3-ethyl-5-phenyl-1,3-benzoxazol-3-ium-2-yl)ethenyl]-N-methylaniline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑类
• 英文名称: N-[(E)-2-(3-ethyl-5-phenyl-1,3-benzoxazol-3-ium-2-yl)ethenyl]-N-methylaniline
• 化学式: C24H23N2O+
• 分子量: 355.5
• InChiKey: OJYWVDKWJDNSKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR
  申请人：Diamond Marc

  公开号：US20110224253A1

  公开（公告）日：2011-09-15

  The present invention provides tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof. The present invention provides a method of using tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof.
• MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY
  申请人：Moon Randall T.

  公开号：US20120040916A1

  公开（公告）日：2012-02-16

  The present invention is directed toward a method of treating a subject for a condition mediated by the Wnt/β-catenin pathway by selecting a subject with a condition mediated by the Wnt/β-catenin pathway and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. A method of similarly inhibiting the Wnt/β-catenin pathway in a subject is also disclosed.
• US8354538B2
  申请人：——

  公开号：US8354538B2

  公开（公告）日：2013-01-15
• US8580773B2
  申请人：——

  公开号：US8580773B2

  公开（公告）日：2013-11-12
• [EN] SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR<br/>[FR] INHIBITEURS DE PETITES MOLÉCULES DU RÉCEPTEUR DE L'ANDROGÈNE
  申请人：UNIV CALIFORNIA

  公开号：WO2009132307A1

  公开（公告）日：2009-10-29

  The present invention provides tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof. The present invention provides a method of using tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof.