(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylsulfonylamino]benzoyl]amino]pentanedioic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylsulfonylamino]benzoyl]amino]pentanedioic acid
• 化学式: C₂₀H₂₂N₈O₇S
• 分子量: 518.5
• InChiKey: PULZJZXQFCSTDJ-ZDUSSCGKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  36
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  253
• 氢给体数：
  5
• 氢受体数：
  14

文献信息

• METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES
  申请人：Translatum Medicus Inc.

  公开号：EP2844250A1

  公开（公告）日：2015-03-11
• [EN] METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES<br/>[FR] PROCÉDÉ DE TRAITEMENT ET DE DIAGNOSTIC DE MALADIES MENANT À LA CÉCITÉ
  申请人：BOYD SHELLEY ROMAYNE

  公开号：WO2013163758A1

  公开（公告）日：2013-11-07

  This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including in the discovery of drugs that are efficacious against these diseases. Diseases include, for example, age related macular degeneration and reticular pseudodrusen disease, and the methods described herein include, for example, the method named delayed near infrared analysis (DNIRA).