methyl N,N-bis(ethylsulfamoyl)carbamate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: methyl N,N-bis(ethylsulfamoyl)carbamate
• 化学式: C₆H₁₅N₃O₆S₂
• 分子量: 289.3
• InChiKey: AZCJAKMPYCDTAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  139
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• [EN] COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LE TRAITEMENT DE MALADIES NEURODÉGÉNÉRATIVES
  申请人：INSERO HEALTH INC

  公开号：WO2013166468A1

  公开（公告）日：2013-11-07

  Huperzine A analog compounds having acetylcholinesterase inhibitor activity are described. The huperzine analogs are used in the treatment of neurodegenerative diseases. Various compositions and methods include an NMDA receptor antagonist and either a mitochondrial protectant or anti-inflammatory agent. The acetylcholinesterase inhibitor may be specific to the G4 isoform of acetylcholinesterase. Methods of treating neurodegenerative diseases by administering a composition having a therapeutically effective amount of one of the acetycholinesterate compounds are described.