Ethyl-dihydroxy-octadecylazanium;chloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Ethyl-dihydroxy-octadecylazanium;chloride
• 英文别名: ethyl-dihydroxy-octadecylazanium;chloride
• 化学式: C20H44ClNO2
• 分子量: 366.0
• InChiKey: UXIVSRDTEKMDDP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.87
• 重原子数：
  24
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] RICE BRAN-LIPIDS BASED FORMULATION AND PROCESS FOR PREPARATION THEREOF FOR SELECTIVE DELIVERY OF GENES TO CANCER CELLS<br/>[FR] FORMULATION À BASE DE LIPIDES DE SON DE RIZ ET SON PROCÉDÉ DE PRÉPARATION EN VUE D'UNE ADMINISTRATION SÉLECTIVE DE GÈNES DANS LES CELLULES CANCÉREUSES
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2013186793A1

  公开（公告）日：2013-12-19

  The present invention relates to a formulation in which glycolipids and phospholipids, isolated from rice bran gum samples, were used in conjunction with gene carrying lipids to test its efficacy in delivering genes to cancer cells selectively. This formulation did not mediate efficient delivery of genes to non-cancerous cells, thus, showing potential use of this formulation to deliver anticancer therapeutics to cancer cells without eliciting treatment related toxicity to normal cells